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Mar. Drugs 2015, 13(12), 7275-7284; doi:10.3390/md13127064

Biotechnological Production of Docosahexaenoic Acid Using Aurantiochytrium limacinum: Carbon Sources Comparison And Growth Characterization

Bioengineering Department, IQS, Ramon Llull University, Via Augusta 390, Barcelona 08017, Spain
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Author to whom correspondence should be addressed.
Academic Editor: Gilles Barnathan
Received: 8 June 2015 / Accepted: 30 November 2015 / Published: 5 December 2015
(This article belongs to the Special Issue Marine Lipids)
View Full-Text   |   Download PDF [471 KB, uploaded 5 December 2015]   |  

Abstract

Aurantiochytrium limacinum, a marine heterotrophic protist/microalga has shown interesting yields of docosahexaenoic acid (DHA) when cultured with different carbon sources: glucose, pure and crude glycerol. A complete study in a lab-scale fermenter allowed for the characterization and comparison of the growth kinetic parameters corresponding to each carbon source. Artificial Marine Medium (AMM) with glucose, pure and crude glycerol offered similar biomass yields. The net growth rates (0.10–0.12 h−1), biomass (0.7–0.8 g cells/g Substrate) and product (0.14–0.15 g DHA/g cells) yields, as well as DHA productivity were similar using the three carbon sources. Viable potential applications to valorize crude glycerol are envisioned to avoid an environmental problem due to the excess of byproduct. View Full-Text
Keywords: glycerol; biodiesel; DHA; fatty acids; PUFA; omega-3 fatty acids; microalgae; bioprocess; nutraceutics glycerol; biodiesel; DHA; fatty acids; PUFA; omega-3 fatty acids; microalgae; bioprocess; nutraceutics
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Abad, S.; Turon, X. Biotechnological Production of Docosahexaenoic Acid Using Aurantiochytrium limacinum: Carbon Sources Comparison And Growth Characterization. Mar. Drugs 2015, 13, 7275-7284.

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