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Mar. Drugs 2015, 13(11), 6838-6865; doi:10.3390/md13116838

Seaweeds as Preventive Agents for Cardiovascular Diseases: From Nutrients to Functional Foods

1
Department of Chemistry & QOPNA, University of Aveiro, Aveiro 3810-193, Portugal
2
Department of Diagnostic and Therapeutic Technologies, School of Health Sciences, Polytechnic Institute of Bragança, Bragança 5300-121, Portugal
3
Department of Technological Science and Development, University of Azores, Ponta Delgada 9501-801, Portugal
*
Author to whom correspondence should be addressed.
Academic Editor: Colin Barrow
Received: 8 August 2015 / Revised: 16 October 2015 / Accepted: 30 October 2015 / Published: 12 November 2015
(This article belongs to the Special Issue Marine Functional Food)
View Full-Text   |   Download PDF [298 KB, uploaded 12 November 2015]   |  

Abstract

Being naturally enriched in key nutrients and in various health-promoting compounds, seaweeds represent promising candidates for the design of functional foods. Soluble dietary fibers, peptides, phlorotannins, lipids and minerals are macroalgae’s major compounds that can hold potential in high-value food products derived from macroalgae, including those directed to the cardiovascular-health promotion. This manuscript revises available reported data focusing the role of diet supplementation of macroalgae, or extracts enriched in bioactive compounds from macroalgae origin, in targeting modifiable markers of cardiovascular diseases (CVDs), like dyslipidemia, oxidative stress, vascular inflammation, hypertension, hypercoagulability and activation of the sympathetic and renin-angiotensin systems, among others. At last, the review also describes several products that have been formulated with the use of whole macroalgae or extracts, along with their claimed cardiovascular-associated benefits. View Full-Text
Keywords: macroalgae; algae; heart; hypertension; atherosclerosis; minerals; peptides; sulfated polysaccharides; bioactive; functional food macroalgae; algae; heart; hypertension; atherosclerosis; minerals; peptides; sulfated polysaccharides; bioactive; functional food
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Cardoso, S.M.; Pereira, O.R.; Seca, A.M.L.; Pinto, D.C.G.A.; Silva, A.M.S. Seaweeds as Preventive Agents for Cardiovascular Diseases: From Nutrients to Functional Foods. Mar. Drugs 2015, 13, 6838-6865.

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