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Mar. Drugs 2014, 12(5), 2816-2826; doi:10.3390/md12052816
Article

Cyclodepsipeptides and Other O-Containing Heterocyclic Metabolites from Beauveria felina EN-135, a Marine-Derived Entomopathogenic Fungus

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Received: 2 February 2014; in revised form: 25 March 2014 / Accepted: 28 April 2014 / Published: 13 May 2014
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Abstract: Bioassay-guided fractionation of a culture extract of Beauveria felina EN-135, an entomopathogenic fungus isolated from a marine bryozoan, led to the isolation of a new cyclodepsipeptide, iso-isariin D (1); two new O-containing heterocyclic compounds that we have named felinones A and B (2 and 3); and four known cyclodepsipeptides (47). The structures were elucidated via spectroscopic analysis, and the absolute configurations of 1 and 2 were determined using single-crystal X-ray diffraction and CD, respectively. All isolated compounds were evaluated for antimicrobial activity and brine-shrimp (Artemia salina) lethality.
Keywords: marine fungus; bryozoan; Beauveria felina; secondary metabolites; bioactivity marine fungus; bryozoan; Beauveria felina; secondary metabolites; bioactivity
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Du, F.-Y.; Li, X.-M.; Zhang, P.; Li, C.-S.; Wang, B.-G. Cyclodepsipeptides and Other O-Containing Heterocyclic Metabolites from Beauveria felina EN-135, a Marine-Derived Entomopathogenic Fungus. Mar. Drugs 2014, 12, 2816-2826.

AMA Style

Du F-Y, Li X-M, Zhang P, Li C-S, Wang B-G. Cyclodepsipeptides and Other O-Containing Heterocyclic Metabolites from Beauveria felina EN-135, a Marine-Derived Entomopathogenic Fungus. Marine Drugs. 2014; 12(5):2816-2826.

Chicago/Turabian Style

Du, Feng-Yu; Li, Xiao-Ming; Zhang, Peng; Li, Chun-Shun; Wang, Bin-Gui. 2014. "Cyclodepsipeptides and Other O-Containing Heterocyclic Metabolites from Beauveria felina EN-135, a Marine-Derived Entomopathogenic Fungus." Mar. Drugs 12, no. 5: 2816-2826.



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