Mar. Drugs 2013, 11(7), 2667-2681; doi:10.3390/md11072667
Article

Production, Characterization, and Antioxidant Activity of Fucoxanthin from the Marine Diatom Odontella aurita

1 Institute of Hydrobiology, Jinan University, Guangzhou 510632, China 2 Laboratory for Algae Research and Biotechnology, College of Technology and Innovation, Arizona State University, 7001 E. Williams Field Road, Mesa, AZ 85212, USA
* Authors to whom correspondence should be addressed.
Received: 23 April 2013; in revised form: 7 June 2013 / Accepted: 8 July 2013 / Published: 23 July 2013
(This article belongs to the Special Issue Bioactive Compounds from Marine Plankton)
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Abstract: The production, characterization, and antioxidant capacity of the carotenoid fucoxanthin from the marine diatom Odontella aurita were investigated. The results showed that low light and nitrogen-replete culture medium enhanced the biosynthesis of fucoxanthin. The maximum biomass concentration of 6.36 g L−1 and maximum fucoxanthin concentration of 18.47 mg g−1 were obtained in cultures grown in a bubble column photobioreactor (Ø 3.0 cm inner diameter), resulting in a fucoxanthin volumetric productivity of 7.96 mg L−1 day−1. A slight reduction in biomass production was observed in the scaling up of O. aurita culture in a flat plate photobioreactor, yet yielded a comparable fucoxanthin volumetric productivity. A rapid method was developed for extraction and purification of fucoxanthin. The purified fucoxanthin was identified as all-trans-fucoxanthin, which exhibited strong antioxidant properties, with the effective concentration for 50% scavenging (EC50) of 1,1-dihpenyl-2-picrylhydrazyl (DPPH) radical and 2,2′-Azino-bis(3-ethylbenzthiazoline-6-sulfonic acid (ABTS) radical being 0.14 and 0.03 mg mL−1, respectively. Our results suggested that O. aurita can be a natural source of fucoxanthin for human health and nutrition.
Keywords: Odontella aurita; fucoxanthin; photobioreactor; antioxidant

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MDPI and ACS Style

Xia, S.; Wang, K.; Wan, L.; Li, A.; Hu, Q.; Zhang, C. Production, Characterization, and Antioxidant Activity of Fucoxanthin from the Marine Diatom Odontella aurita. Mar. Drugs 2013, 11, 2667-2681.

AMA Style

Xia S, Wang K, Wan L, Li A, Hu Q, Zhang C. Production, Characterization, and Antioxidant Activity of Fucoxanthin from the Marine Diatom Odontella aurita. Marine Drugs. 2013; 11(7):2667-2681.

Chicago/Turabian Style

Xia, Song; Wang, Ke; Wan, Linglin; Li, Aifen; Hu, Qiang; Zhang, Chengwu. 2013. "Production, Characterization, and Antioxidant Activity of Fucoxanthin from the Marine Diatom Odontella aurita." Mar. Drugs 11, no. 7: 2667-2681.

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