Mar. Drugs 2013, 11(7), 2667-2681; doi:10.3390/md11072667
Article

Production, Characterization, and Antioxidant Activity of Fucoxanthin from the Marine Diatom Odontella aurita

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Received: 23 April 2013; in revised form: 7 June 2013 / Accepted: 8 July 2013 / Published: 23 July 2013
(This article belongs to the Special Issue Bioactive Compounds from Marine Plankton)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: The production, characterization, and antioxidant capacity of the carotenoid fucoxanthin from the marine diatom Odontella aurita were investigated. The results showed that low light and nitrogen-replete culture medium enhanced the biosynthesis of fucoxanthin. The maximum biomass concentration of 6.36 g L−1 and maximum fucoxanthin concentration of 18.47 mg g−1 were obtained in cultures grown in a bubble column photobioreactor (Ø 3.0 cm inner diameter), resulting in a fucoxanthin volumetric productivity of 7.96 mg L−1 day−1. A slight reduction in biomass production was observed in the scaling up of O. aurita culture in a flat plate photobioreactor, yet yielded a comparable fucoxanthin volumetric productivity. A rapid method was developed for extraction and purification of fucoxanthin. The purified fucoxanthin was identified as all-trans-fucoxanthin, which exhibited strong antioxidant properties, with the effective concentration for 50% scavenging (EC50) of 1,1-dihpenyl-2-picrylhydrazyl (DPPH) radical and 2,2′-Azino-bis(3-ethylbenzthiazoline-6-sulfonic acid (ABTS) radical being 0.14 and 0.03 mg mL−1, respectively. Our results suggested that O. aurita can be a natural source of fucoxanthin for human health and nutrition.
Keywords: Odontella aurita; fucoxanthin; photobioreactor; antioxidant
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MDPI and ACS Style

Xia, S.; Wang, K.; Wan, L.; Li, A.; Hu, Q.; Zhang, C. Production, Characterization, and Antioxidant Activity of Fucoxanthin from the Marine Diatom Odontella aurita. Mar. Drugs 2013, 11, 2667-2681.

AMA Style

Xia S, Wang K, Wan L, Li A, Hu Q, Zhang C. Production, Characterization, and Antioxidant Activity of Fucoxanthin from the Marine Diatom Odontella aurita. Marine Drugs. 2013; 11(7):2667-2681.

Chicago/Turabian Style

Xia, Song; Wang, Ke; Wan, Linglin; Li, Aifen; Hu, Qiang; Zhang, Chengwu. 2013. "Production, Characterization, and Antioxidant Activity of Fucoxanthin from the Marine Diatom Odontella aurita." Mar. Drugs 11, no. 7: 2667-2681.


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