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Mar. Drugs 2013, 11(12), 4741-4750; doi:10.3390/md11124741
Article

New Sinularianin Sesquiterpenes from Soft Coral Sinularia sp.

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Received: 5 September 2013; in revised form: 4 November 2013 / Accepted: 4 November 2013 / Published: 2 December 2013
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Abstract: Four new sesquiterpenes, sinularianins C–F (36), together with known sinularianins A (1) and B (2) were identified from a South China Sea soft coral Sinularia sp. Compounds 16 were evaluated for inhibition of NF-κB activation using the cell-based HEK293 NF-κB luciferase reporter gene assay. Compounds 1 and 4 were exhibited a potent effect with inhibitory rates of 41.3% and 43.0% at the concentration of 10 µg/mL, respectively.
Keywords: soft coral; Sinularia sp.; sesquiterpenes; sinularianins; NF-κB soft coral; Sinularia sp.; sesquiterpenes; sinularianins; NF-κB
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Yang, B.; Liao, S.; Lin, X.; Wang, J.; Liu, J.; Zhou, X.; Yang, X.; Liu, Y. New Sinularianin Sesquiterpenes from Soft Coral Sinularia sp.. Mar. Drugs 2013, 11, 4741-4750.

AMA Style

Yang B, Liao S, Lin X, Wang J, Liu J, Zhou X, Yang X, Liu Y. New Sinularianin Sesquiterpenes from Soft Coral Sinularia sp.. Marine Drugs. 2013; 11(12):4741-4750.

Chicago/Turabian Style

Yang, Bin; Liao, Shengrong; Lin, Xiuping; Wang, Junfeng; Liu, Juan; Zhou, Xuefeng; Yang, Xianwen; Liu, Yonghong. 2013. "New Sinularianin Sesquiterpenes from Soft Coral Sinularia sp.." Mar. Drugs 11, no. 12: 4741-4750.



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