Mar. Drugs 2013, 11(12), 4741-4750; doi:10.3390/md11124741
Article

New Sinularianin Sesquiterpenes from Soft Coral Sinularia sp.

email, email, email, email, email, email, email and * email
Received: 5 September 2013; in revised form: 4 November 2013 / Accepted: 4 November 2013 / Published: 2 December 2013
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Four new sesquiterpenes, sinularianins C–F (36), together with known sinularianins A (1) and B (2) were identified from a South China Sea soft coral Sinularia sp. Compounds 16 were evaluated for inhibition of NF-κB activation using the cell-based HEK293 NF-κB luciferase reporter gene assay. Compounds 1 and 4 were exhibited a potent effect with inhibitory rates of 41.3% and 43.0% at the concentration of 10 µg/mL, respectively.
Keywords: soft coral; Sinularia sp.; sesquiterpenes; sinularianins; NF-κB
PDF Full-text Download PDF Full-Text [825 KB, uploaded 2 December 2013 09:38 CET]

Export to BibTeX |
EndNote


MDPI and ACS Style

Yang, B.; Liao, S.; Lin, X.; Wang, J.; Liu, J.; Zhou, X.; Yang, X.; Liu, Y. New Sinularianin Sesquiterpenes from Soft Coral Sinularia sp.. Mar. Drugs 2013, 11, 4741-4750.

AMA Style

Yang B, Liao S, Lin X, Wang J, Liu J, Zhou X, Yang X, Liu Y. New Sinularianin Sesquiterpenes from Soft Coral Sinularia sp.. Marine Drugs. 2013; 11(12):4741-4750.

Chicago/Turabian Style

Yang, Bin; Liao, Shengrong; Lin, Xiuping; Wang, Junfeng; Liu, Juan; Zhou, Xuefeng; Yang, Xianwen; Liu, Yonghong. 2013. "New Sinularianin Sesquiterpenes from Soft Coral Sinularia sp.." Mar. Drugs 11, no. 12: 4741-4750.

Mar. Drugs EISSN 1660-3397 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert