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Mar. Drugs 2013, 11(1), 114-123; doi:10.3390/md11010114
Article

A New Spatane Diterpenoid from the Cultured Soft Coral Sinularia leptoclados

1,†
, 2,†
, 3
, 4
 and 5,*
Received: 27 November 2012; in revised form: 11 December 2012 / Accepted: 24 December 2012 / Published: 10 January 2013
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Abstract: A new spatane diterpenoid, leptoclalin A (1), along with two previously reported known norcembranoid diterpenes (2 and 3), were isolated from a cultured soft coral Sinularia leptoclados. The structures were determined by extensive spectroscopic analyses and by comparison with the spectral data of related known compounds. Metabolite 1 is rarely found in spatane skeletons reported from soft corals. In addition, compound 1 exhibited weak cytotoxicity towards human tumor cell lines T-47 D and K-562.
Keywords: spatane diterpenoid; soft coral; Sinularia leptoclados spatane diterpenoid; soft coral; Sinularia leptoclados
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Tsai, T.-C.; Wu, Y.-J.; Su, J.-H.; Lin, W.-T.; Lin, Y.-S. A New Spatane Diterpenoid from the Cultured Soft Coral Sinularia leptoclados. Mar. Drugs 2013, 11, 114-123.

AMA Style

Tsai T-C, Wu Y-J, Su J-H, Lin W-T, Lin Y-S. A New Spatane Diterpenoid from the Cultured Soft Coral Sinularia leptoclados. Marine Drugs. 2013; 11(1):114-123.

Chicago/Turabian Style

Tsai, Tsung-Chang; Wu, Yu-Jen; Su, Jui-Hsin; Lin, Wei-Tung; Lin, Yun-Sheng. 2013. "A New Spatane Diterpenoid from the Cultured Soft Coral Sinularia leptoclados." Mar. Drugs 11, no. 1: 114-123.


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