Mar. Drugs 2012, 10(7), 1572-1581; doi:10.3390/md10071572
Article

Lochmolins A–G, New Sesquiterpenoids from the Soft Coral Sinularia lochmodes

Yen-Ju Tseng 1 email, Kuo-Ping Shen 2 email, Hui-Li Lin 3 email, Chiung-Yao Huang 1 email, Chang-Feng Dai 4 email and Jyh-Horng Sheu 1,5,* email
1 Department of Marine Biotechnology and Resources, National Sun Yat-sen University, Kaohsiung 804, Taiwan 2 Department of Nursing, Meiho University, Pingtung 912, Taiwan 3 Department of Food and Nutrition, Meiho University, Pingtung 912, Taiwan 4 Institute of Oceanography, National Taiwan University, Taipei 112, Taiwan 5 Division of Marine Biotechnology, Asia-Pacific Ocean Research Center, National Sun Yat-sen University, Kaohsiung 804, Taiwan
* Author to whom correspondence should be addressed.
Received: 15 June 2012; in revised form: 6 July 2012 / Accepted: 13 July 2012 / Published: 20 July 2012
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Abstract: Seven new sesquiterpenoids, lochmolins A–G (1–7), were isolated from a Taiwanese soft coral Sinularia lochmodes. The structures of these metabolites were elucidated by extensive spectroscopic study. Compounds 1–4 were found to inhibit the accumulation of the LPS-induced pro-inflammatory COX-2 protein in RAW264.7 macrophage cells.
Keywords: soft coral; Sinularia lochmodes; sesquiterpenes; aromadendrane; germacrane

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MDPI and ACS Style

Tseng, Y.-J.; Shen, K.-P.; Lin, H.-L.; Huang, C.-Y.; Dai, C.-F.; Sheu, J.-H. Lochmolins A–G, New Sesquiterpenoids from the Soft Coral Sinularia lochmodes. Mar. Drugs 2012, 10, 1572-1581.

AMA Style

Tseng Y-J, Shen K-P, Lin H-L, Huang C-Y, Dai C-F, Sheu J-H. Lochmolins A–G, New Sesquiterpenoids from the Soft Coral Sinularia lochmodes. Marine Drugs. 2012; 10(7):1572-1581.

Chicago/Turabian Style

Tseng, Yen-Ju; Shen, Kuo-Ping; Lin, Hui-Li; Huang, Chiung-Yao; Dai, Chang-Feng; Sheu, Jyh-Horng. 2012. "Lochmolins A–G, New Sesquiterpenoids from the Soft Coral Sinularia lochmodes." Mar. Drugs 10, no. 7: 1572-1581.

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