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Pseudoalteromone B: A Novel 15C Compound from a Marine Bacterium Pseudoalteromonas sp. CGH2XX
Department of Life Science and Institute of Biotechnology, National Dong Hwa University, Hualien 974, Taiwan
Graduate Institute of Marine Biotechnology, National Dong Hwa University, Pingtung 944, Taiwan
National Museum of Marine Biology and Aquarium, Pingtung 944, Taiwan
Graduate Institute of Natural Products, Chang Gung University, Taoyuan 333, Taiwan
Department of Marine Biotechnology and Resources and Division of Marine Biotechnology, Asia-Pacific Ocean Research Center, National Sun Yat-sen University, Kaohsiung 804, Taiwan
* Authors to whom correspondence should be addressed.
Received: 12 June 2012; in revised form: 12 July 2012 / Accepted: 12 July 2012 / Published: 20 July 2012
Abstract: A novel 15C compound, pseudoalteromone B (1), possessing a novel carbon skeleton, was obtained from a marine bacterium Pseudoalteromonas sp. CGH2XX. This bacterium was originally isolated from a cultured-type octocoral Lobophytum crassum, that was growing in cultivating tanks equipped with a flow-through sea water system. The structure of 1 was established by spectroscopic methods. Pseudoalteromone B (1) displayed a modestly inhibitory effect on the release of elastase by human neutrophils.
Keywords: pseudoalteromone; Pseudoalteromonas; anti-inflammatory; Lobophytum crassum; elastase
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Chen, Y.-H.; Kuo, J.; Su, J.-H.; Hwang, T.-L.; Chen, Y.-H.; Lee, C.-H.; Weng, C.-F.; Sung, P.-J. Pseudoalteromone B: A Novel 15C Compound from a Marine Bacterium Pseudoalteromonas sp. CGH2XX. Mar. Drugs 2012, 10, 1566-1571.
Chen Y-H, Kuo J, Su J-H, Hwang T-L, Chen Y-H, Lee C-H, Weng C-F, Sung P-J. Pseudoalteromone B: A Novel 15C Compound from a Marine Bacterium Pseudoalteromonas sp. CGH2XX. Marine Drugs. 2012; 10(7):1566-1571.
Chen, Yu-Hsin; Kuo, Jimmy; Su, Jui-Hsin; Hwang, Tsong-Long; Chen, Yung-Husan; Lee, Chia-Hung; Weng, Ching-Feng; Sung, Ping-Jyun. 2012. "Pseudoalteromone B: A Novel 15C Compound from a Marine Bacterium Pseudoalteromonas sp. CGH2XX." Mar. Drugs 10, no. 7: 1566-1571.