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Mar. Drugs 2012, 10(7), 1566-1571; doi:10.3390/md10071566
Article

Pseudoalteromone B: A Novel 15C Compound from a Marine Bacterium Pseudoalteromonas sp. CGH2XX

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1 Department of Life Science and Institute of Biotechnology, National Dong Hwa University, Hualien 974, Taiwan 2 Graduate Institute of Marine Biotechnology, National Dong Hwa University, Pingtung 944, Taiwan 3 National Museum of Marine Biology and Aquarium, Pingtung 944, Taiwan 4 Graduate Institute of Natural Products, Chang Gung University, Taoyuan 333, Taiwan 5 Department of Marine Biotechnology and Resources and Division of Marine Biotechnology, Asia-Pacific Ocean Research Center, National Sun Yat-sen University, Kaohsiung 804, Taiwan
* Authors to whom correspondence should be addressed.
Received: 12 June 2012 / Revised: 12 July 2012 / Accepted: 12 July 2012 / Published: 20 July 2012
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Abstract

A novel 15C compound, pseudoalteromone B (1), possessing a novel carbon skeleton, was obtained from a marine bacterium Pseudoalteromonas sp. CGH2XX. This bacterium was originally isolated from a cultured-type octocoral Lobophytum crassum, that was growing in cultivating tanks equipped with a flow-through sea water system. The structure of 1 was established by spectroscopic methods. Pseudoalteromone B (1) displayed a modestly inhibitory effect on the release of elastase by human neutrophils.
Keywords: pseudoalteromone; Pseudoalteromonas; anti-inflammatory; Lobophytum crassum; elastase pseudoalteromone; Pseudoalteromonas; anti-inflammatory; Lobophytum crassum; elastase
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
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Chen, Y.-H.; Kuo, J.; Su, J.-H.; Hwang, T.-L.; Chen, Y.-H.; Lee, C.-H.; Weng, C.-F.; Sung, P.-J. Pseudoalteromone B: A Novel 15C Compound from a Marine Bacterium Pseudoalteromonas sp. CGH2XX. Mar. Drugs 2012, 10, 1566-1571.

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