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Mar. Drugs 2012, 10(2), 403-416; doi:10.3390/md10020403
Article

Antioxidant Activity of Hawaiian Marine Algae

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Received: 5 December 2011; in revised form: 6 February 2012 / Accepted: 6 February 2012 / Published: 15 February 2012
(This article belongs to the Special Issue Marine Carotenoids and Oxidative Stress)
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Abstract: Marine algae are known to contain a wide variety of bioactive compounds, many of which have commercial applications in pharmaceutical, medical, cosmetic, nutraceutical, food and agricultural industries. Natural antioxidants, found in many algae, are important bioactive compounds that play an important role against various diseases and ageing processes through protection of cells from oxidative damage. In this respect, relatively little is known about the bioactivity of Hawaiian algae that could be a potential natural source of such antioxidants. The total antioxidant activity of organic extracts of 37 algal samples, comprising of 30 species of Hawaiian algae from 27 different genera was determined. The activity was determined by employing the FRAP (Ferric Reducing Antioxidant Power) assays. Of the algae tested, the extract of Turbinaria ornata was found to be the most active. Bioassay-guided fractionation of this extract led to the isolation of a variety of different carotenoids as the active principles. The major bioactive antioxidant compound was identified as the carotenoid fucoxanthin. These results show, for the first time, that numerous Hawaiian algae exhibit significant antioxidant activity, a property that could lead to their application in one of many useful healthcare or related products as well as in chemoprevention of a variety of diseases including cancer.
Keywords: antioxidant activity; algae; Hawaii; Turbinaria; carotenoids; fucoxanthin; chemoprevention antioxidant activity; algae; Hawaii; Turbinaria; carotenoids; fucoxanthin; chemoprevention
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Kelman, D.; Posner, E.K.; McDermid, K.J.; Tabandera, N.K.; Wright, P.R.; Wright, A.D. Antioxidant Activity of Hawaiian Marine Algae. Mar. Drugs 2012, 10, 403-416.

AMA Style

Kelman D, Posner EK, McDermid KJ, Tabandera NK, Wright PR, Wright AD. Antioxidant Activity of Hawaiian Marine Algae. Marine Drugs. 2012; 10(2):403-416.

Chicago/Turabian Style

Kelman, Dovi; Posner, Ellen Kromkowski; McDermid, Karla J.; Tabandera, Nicole K.; Wright, Patrick R.; Wright, Anthony D. 2012. "Antioxidant Activity of Hawaiian Marine Algae." Mar. Drugs 10, no. 2: 403-416.


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