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Pharmaceuticals 2013, 6(5), 681-688; doi:10.3390/ph6050681

Evolution of Biologics Screening Technologies

MedImmune Ltd, Milstein Building, Granta Park, Cambridge CB21 6GH, UK
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Received: 5 February 2013 / Revised: 23 April 2013 / Accepted: 8 May 2013 / Published: 14 May 2013
(This article belongs to the Special Issue Biologics)
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Abstract

Screening for biologics, in particular antibody drugs, has evolved significantly over the last 20 years. Initially, the screening processes and technologies from many years experience with small molecules were adopted and modified to suit the needs of biologics discovery. Since then, antibody drug discovery has matured significantly and is today investing earlier in new technologies that commercial suppliers are now developing specifically to meet the growing needs of large molecule screening. Here, we review the evolution of screening and automation technologies employed in antibody discovery and highlight the benefits that these changes have brought. View Full-Text
Keywords: high throughput screening; assay technologies; therapeutic antibodies high throughput screening; assay technologies; therapeutic antibodies
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This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Cariuk, P.; Gardener, M.J.; Vaughan, T.J. Evolution of Biologics Screening Technologies. Pharmaceuticals 2013, 6, 681-688.

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