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Cannabinoids and Viral Infections
Department of Biology, Center for Neural Science, NYU Cancer Institute and Department of Microbiology, New York University, 100 Washington Square East, New York, NY, 10003, USA
Received: 21 May 2010; in revised form: 28 May 2010 / Accepted: 9 June 2010 / Published: 9 June 2010
Abstract: Exogenous cannabinoids or receptor antagonists may influence many cellular and systemic host responses. The anti-inflammatory activity of cannabinoids may compromise host inflammatory responses to acute viral infections, but may be beneficial in persistent infections. In neurons, where innate antiviral/pro-resolution responses include the activation of NOS-1, inhibition of Ca2+ activity by cannabinoids, increased viral replication and disease. This review examines the effect(s) of cannabinoids and their antagonists in viral infections.
Keywords: pathogens; virus infection; immunomodulation; inflammation
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Cite This Article
MDPI and ACS Style
Reiss, C.S. Cannabinoids and Viral Infections. Pharmaceuticals 2010, 3, 1873-1886.
Reiss CS. Cannabinoids and Viral Infections. Pharmaceuticals. 2010; 3(6):1873-1886.
Reiss, Carol Shoshkes. 2010. "Cannabinoids and Viral Infections." Pharmaceuticals 3, no. 6: 1873-1886.