Next Article in Journal
In Response to: ‘Impact of Glycosylation on Effector Functions of Therapeutic IgG’ (Pharmaceuticals 2010, 3, 146–157)
Next Article in Special Issue
Cannabinoid-Induced Hyperemesis: A Conundrum—From Clinical Recognition to Basic Science Mechanisms
Previous Article in Journal
Use of p38 MAPK Inhibitors for the Treatment of Werner Syndrome
Pharmaceuticals 2010, 3(6), 1873-1886; doi:10.3390/ph3061873
Review

Cannabinoids and Viral Infections

Received: 21 May 2010 / Revised: 28 May 2010 / Accepted: 9 June 2010 / Published: 9 June 2010
(This article belongs to the Special Issue Cannabinoids)
View Full-Text   |   Download PDF [127 KB, uploaded 9 June 2010]   |   Browse Figure

Abstract

Exogenous cannabinoids or receptor antagonists may influence many cellular and systemic host responses. The anti-inflammatory activity of cannabinoids may compromise host inflammatory responses to acute viral infections, but may be beneficial in persistent infections. In neurons, where innate antiviral/pro-resolution responses include the activation of NOS-1, inhibition of Ca2+ activity by cannabinoids, increased viral replication and disease. This review examines the effect(s) of cannabinoids and their antagonists in viral infections.
Keywords: pathogens; virus infection; immunomodulation; inflammation pathogens; virus infection; immunomodulation; inflammation
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Share & Cite This Article

Further Mendeley | CiteULike
Export to BibTeX |
EndNote
MDPI and ACS Style

Reiss, C.S. Cannabinoids and Viral Infections. Pharmaceuticals 2010, 3, 1873-1886.

View more citation formats

Related Articles

Article Metrics

For more information on the journal, click here

Comments

Cited By

[Return to top]
Pharmaceuticals EISSN 1424-8247 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert