Pharmaceuticals 2009, 2(3), 150-167; doi:10.3390/ph2030150
Review

Mitochondrial Medicine and the Neurodegenerative Mitochondriopathies

Received: 19 November 2009; in revised form: 27 November 2009 / Accepted: 2 December 2009 / Published: 3 December 2009
(This article belongs to the Special Issue Mitochondrial Drugs for Neurodegenerative Diseases)
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Abstract: Neurodegenerative diseases are a common late-life scourge for which diseasemodifying treatments are sorely needed. Mitochondrial perturbation is commonly observed in these diseases, so pursuing treatment development strategies that target mitochondria or processes affected by mitochondria seems reasonable. This review discusses the rationale underlying past and current efforts to treat neurodegenerative diseases using mitochondrial medicine, and tries to predict how future efforts might proceed.
Keywords: mitochondria; mitochondrial biogenesis; mitochondriopathies; neurodegenerative diseases; oxidative stress
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Swerdlow, R.H. Mitochondrial Medicine and the Neurodegenerative Mitochondriopathies. Pharmaceuticals 2009, 2, 150-167.

AMA Style

Swerdlow RH. Mitochondrial Medicine and the Neurodegenerative Mitochondriopathies. Pharmaceuticals. 2009; 2(3):150-167.

Chicago/Turabian Style

Swerdlow, Russell H. 2009. "Mitochondrial Medicine and the Neurodegenerative Mitochondriopathies." Pharmaceuticals 2, no. 3: 150-167.


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