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Sensors 2009, 9(12), 10270-10290; doi:10.3390/s91210270
Article

Nonrigid Registration of Brain Tumor Resection MR Images Based on Joint Saliency Map and Keypoint Clustering

 and *
Received: 23 October 2009; in revised form: 1 December 2009 / Accepted: 9 December 2009 / Published: 17 December 2009
(This article belongs to the Special Issue Image Sensors)
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Abstract: This paper proposes a novel global-to-local nonrigid brain MR image registration to compensate for the brain shift and the unmatchable outliers caused by the tumor resection. The mutual information between the corresponding salient structures, which are enhanced by the joint saliency map (JSM), is maximized to achieve a global rigid registration of the two images. Being detected and clustered at the paired contiguous matching areas in the globally registered images, the paired pools of DoG keypoints in combination with the JSM provide a useful cluster-to-cluster correspondence to guide the local control-point correspondence detection and the outlier keypoint rejection. Lastly, a quasi-inverse consistent deformation is smoothly approximated to locally register brain images through the mapping the clustered control points by compact support radial basis functions. The 2D implementation of the method can model the brain shift in brain tumor resection MR images, though the theory holds for the 3D case.
Keywords: nonrigid registration; tumor resection; keypoint; outlier; local large deformation; brain shift; clustering nonrigid registration; tumor resection; keypoint; outlier; local large deformation; brain shift; clustering
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Gu, Z.; Qin, B. Nonrigid Registration of Brain Tumor Resection MR Images Based on Joint Saliency Map and Keypoint Clustering. Sensors 2009, 9, 10270-10290.

AMA Style

Gu Z, Qin B. Nonrigid Registration of Brain Tumor Resection MR Images Based on Joint Saliency Map and Keypoint Clustering. Sensors. 2009; 9(12):10270-10290.

Chicago/Turabian Style

Gu, Zhijun; Qin, Binjie. 2009. "Nonrigid Registration of Brain Tumor Resection MR Images Based on Joint Saliency Map and Keypoint Clustering." Sensors 9, no. 12: 10270-10290.


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