Sensors 2008, 8(6), 3624-3632; doi:10.3390/s8063624
Article

DNA Extraction Systematics for Spectroscopic Studies

Bianca Fogazza Palma 1 email, Amanda Borges Ferrari 1 email, Renata Andrade Bitar 1 email, Maria Angélica Gargione Cardoso 1 email, Airton A. Martin 1 email and Herculano Da Silva Martinho 2,* email
1 Instituto de Pesquisa & Desenvolvimento, Universidade do Vale do Paraíba, Av. Shishima Hifumi, 2911, 12244-000, São José dos Campos, São Paulo, Brazil 2 Centro de Ciências Naturais e Humanas, Universidade Federal do ABC, Rua Catequese 242, 09090-400, Santo André, São Paulo, Brazil
* Author to whom correspondence should be addressed.
Received: 29 April 2008; in revised form: 19 May 2008 / Accepted: 20 May 2008 / Published: 1 June 2008
(This article belongs to the Special Issue Bioanalysis in Vivo/in Vitro)
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Abstract: Study of genetic material allows the comprehension the origin of the many biochemical changes that follow diseases, like cancer, promoting the development of early preventive inquiry and more efficient individual treatments. Raman spectroscopy can be an important tool in DNA study, since it allows probe molecular vibrations of genetic material in a fast way. The present work established a systematic way for extract DNA in suitable concentrations and structural integrity allowing studies by Raman spectroscopy or other spectroscopic technique, including bio-analytical sensors for probing genetic alterations.
Keywords: DNA; Raman spectroscopy; Cancer.

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Cite This Article

MDPI and ACS Style

Palma, B.F.; Ferrari, A.B.; Bitar, R.A.; Cardoso, M.A.G.; Martin, A.A.; Da Silva Martinho, H. DNA Extraction Systematics for Spectroscopic Studies. Sensors 2008, 8, 3624-3632.

AMA Style

Palma BF, Ferrari AB, Bitar RA, Cardoso MAG, Martin AA, Da Silva Martinho H. DNA Extraction Systematics for Spectroscopic Studies. Sensors. 2008; 8(6):3624-3632.

Chicago/Turabian Style

Palma, Bianca F.; Ferrari, Amanda B.; Bitar, Renata A.; Cardoso, Maria A.G.; Martin, Airton A.; Da Silva Martinho, Herculano. 2008. "DNA Extraction Systematics for Spectroscopic Studies." Sensors 8, no. 6: 3624-3632.

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