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Porous Silicon Based Resonant Mirrors for Biochemical Sensing
Institute for Microelectronics and Microsystems – Unit of Naples – National Council of Research, Via P. Castellino 111, 80131 Napoli, Italy
Department of Physical Sciences, University of Naples “Federico II”, Via Cinthia, 80126 Naples, Italy
Department of Organic Chemistry and Biochemistry, University of Naples “Federico II”, Via Cinthia, 80128 Napoli, Italy
Department of Biochemistry and Medical Biotechnologies, University of Naples “Federico II”, Via S. Pansini 5, 80131 Napoli, Italy
* Author to whom correspondence should be addressed.
Received: 6 June 2008; in revised form: 6 October 2008 / Accepted: 21 October 2008 / Published: 23 October 2008
Abstract: We report on our preliminary results in the realization and characterization of a porous silicon (PSi) resonant mirror (RM) for optical biosensing. We have numerically and experimentally studied the coupling between the electromagnetic field, totally reflected at the base of a high refractive index prism, and the optical modes of a PSi waveguide. This configuration is very sensitive to changes in the refractive index and/or in thickness of the sensor surface. Due to the high specific area of the PSi waveguide, very low DNA concentrations can be detected confirming that the RM could be a very sensitive and labelfree optical biosensor.
Keywords: DNA Optical Biosensors; Porous Silicon; Resonant Mirrors
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De Tommasi, E.; De Stefano, L.; Rea, I.; Di Sarno, V.; Rotiroti, L.; Arcari, P.; Lamberti, A.; Sanges, C.; Rendina, I. Porous Silicon Based Resonant Mirrors for Biochemical Sensing. Sensors 2008, 8, 6549-6556.
De Tommasi E, De Stefano L, Rea I, Di Sarno V, Rotiroti L, Arcari P, Lamberti A, Sanges C, Rendina I. Porous Silicon Based Resonant Mirrors for Biochemical Sensing. Sensors. 2008; 8(10):6549-6556.
De Tommasi, Edoardo; De Stefano, Luca; Rea, Ilaria; Di Sarno, Valentina; Rotiroti, Lucia; Arcari, Paolo; Lamberti, Annalisa; Sanges, Carmen; Rendina, Ivo. 2008. "Porous Silicon Based Resonant Mirrors for Biochemical Sensing." Sensors 8, no. 10: 6549-6556.