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• De Tommasi, E
• De Stefano, L
• Rea, I
• Di Sarno, V
• Rotiroti, L
• Arcari, P
• Lamberti, A
• Sanges, C
• Rendina, I
• [+] on Google Scholar
• De Tommasi, E
• De Stefano, L
• Rea, I
• Di Sarno, V
• Rotiroti, L
• Arcari, P
• Lamberti, A
• Sanges, C
• Rendina, I
• [+] on PubMed
• De Tommasi, E
• De Stefano, L
• Rea, I
• Di Sarno, V
• Rotiroti, L
• Arcari, P
• Lamberti, A
• Sanges, C
• Rendina, I

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Sensors 2008, 8(10), 6549-6556; doi:10.3390/s8106549

Article

Porous Silicon Based Resonant Mirrors for Biochemical Sensing

Edoardo De Tommasi ^1,* , Luca De Stefano ¹ , Ilaria Rea ^1,2 , Valentina Di Sarno ^1,2 , Lucia Rotiroti ^1,3 , Paolo Arcari ⁴ , Annalisa Lamberti ⁴ , Carmen Sanges ⁴  and Ivo Rendina ¹

¹ Institute for Microelectronics and Microsystems – Unit of Naples – National Council of Research, Via P. Castellino 111, 80131 Napoli, Italy ² Department of Physical Sciences, University of Naples “Federico II”, Via Cinthia, 80126 Naples, Italy ³ Department of Organic Chemistry and Biochemistry, University of Naples “Federico II”, Via Cinthia, 80128 Napoli, Italy ⁴ Department of Biochemistry and Medical Biotechnologies, University of Naples “Federico II”, Via S. Pansini 5, 80131 Napoli, Italy

* Author to whom correspondence should be addressed.

Received: 6 June 2008; in revised form: 6 October 2008 / Accepted: 21 October 2008 / Published: 23 October 2008

(This article belongs to the Section Biosensors)

Download PDF Full-Text [282 KB, uploaded 23 October 2008 11:45 CEST]

Abstract: We report on our preliminary results in the realization and characterization of a porous silicon (PSi) resonant mirror (RM) for optical biosensing. We have numerically and experimentally studied the coupling between the electromagnetic field, totally reflected at the base of a high refractive index prism, and the optical modes of a PSi waveguide. This configuration is very sensitive to changes in the refractive index and/or in thickness of the sensor surface. Due to the high specific area of the PSi waveguide, very low DNA concentrations can be detected confirming that the RM could be a very sensitive and labelfree optical biosensor.

Keywords: DNA Optical Biosensors; Porous Silicon; Resonant Mirrors

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