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Guided-Wave Optical Biosensors
Photonics Research Group, Dipartimento di Elettrotecnica ed Elettronica, Politecnico di Bari, via Edoardo Orabona n. 4, 70125 Bari, Italy
Photonics Research Group, Dipartimento di Ingegneria dell’Ambiente e per lo Sviluppo Sostenibile, Politecnico di Bari, viale del Turismo n. 8, 74100 Taranto, Italy
* Author to whom correspondence should be addressed.
Received: 23 March 2007; in revised form: / Accepted: 24 April 2007 / Published: 25 April 2007
Abstract: Guided-wave optical biosensors are reviewed in this paper. Advantages related to optical technologies are presented and integrated architectures are investigated in detail. Main classes of bio receptors and the most attractive optical transduction mechanisms are discussed. The possibility to use Mach-Zehnder and Young interferometers, microdisk and microring resonators, surface plasmon resonance, hollow and antiresonant waveguides, and Bragg gratings to realize very sensitive and selective, ultra-compact and fast biosensors is discussed. Finally, CMOS-compatible technologies are proved to be the most attractive for fabrication of guided-wave photonic biosensors.
Keywords: Biosensors; Surface Plasmon Resonance; Mach-Zehnder interferometers; Microdisk and Microring; Photonic technologies
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Cite This Article
MDPI and ACS Style
Passaro, V.M.N.; Dell’Olio, F.; Casamassima, B.; De Leonardis, F. Guided-Wave Optical Biosensors. Sensors 2007, 7, 508-536.
Passaro VMN, Dell’Olio F, Casamassima B, De Leonardis F. Guided-Wave Optical Biosensors. Sensors. 2007; 7(4):508-536.
Passaro, Vittorio M.N.; Dell’Olio, Francesco; Casamassima, Biagio; De Leonardis, Francesco. 2007. "Guided-Wave Optical Biosensors." Sensors 7, no. 4: 508-536.