Aspartate Aminotransferase (AST/GOT) and Alanine Aminotransferase (ALT/GPT) Detection Techniques

doi:10.3390/s6070756

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Sensors 2006, 6(7), 756-782; doi:10.3390/s6070756

Review

Aspartate Aminotransferase (AST/GOT) and Alanine Aminotransferase (ALT/GPT) Detection Techniques

Xing-Jiu Huang ¹ , Yang-Kyu Choi ¹^,* , Hyung-Soon Im ¹, Oktay Yarimaga ¹, Euisik Yoon ¹ and Hak-Sung Kim ²

¹ Department of Electrical Engineering and Computer Science, Korea Advanced Institute of Science and Technology, 373-1 Guseong-dong, Yuseong-gu, Daejeon, South Korea ² Department of Biological Sciences, Korea Advanced Institute of Science and Technology, 373-1 Guseong-dong, Yuseong-gu, Daejeon, South Korea

* Author to whom correspondence should be addressed.

Received: 6 May 2006 / Accepted: 30 July 2006 / Published: 31 July 2006

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Abstract: The levels of aspartate aminotransferase (AST/GOT) and alanineaminotransferase (ALT/GPT) in serum can help people diagnose body tissues especially theheart and the liver are injured or not. This article provides a comprehensive review ofresearch activities that concentrate on AST/GOT and ALT/GPT detection techniques due totheir clinical importance. The detection techniques include colorimetric, spectrophotometric,chemiluminescence, chromatography, fluorescence and UV absorbance, radiochemical, andelectrochemical techniques. We devote the most attention on experimental principle. Insome methods a few representative devices and important conclusions are presented.

Keywords: aspartate aminotransferase (AST/GOT); alanine aminotransferase (ALT/GPT); detection techniques.

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Cite This Article

MDPI and ACS Style

Huang, X.-J.; Choi, Y.-K.; Im, H.-S.; Yarimaga, O.; Yoon, E.; Kim, H.-S. Aspartate Aminotransferase (AST/GOT) and Alanine Aminotransferase (ALT/GPT) Detection Techniques. Sensors 2006, 6, 756-782.

AMA Style

Huang X.-J., Choi Y.-K., Im H.-S., Yarimaga O., Yoon E., Kim H.-S. Aspartate Aminotransferase (AST/GOT) and Alanine Aminotransferase (ALT/GPT) Detection Techniques. Sensors. 2006; 6(7):756-782.

Chicago/Turabian Style

Huang, Xing-Jiu; Choi, Yang-Kyu; Im, Hyung-Soon; Yarimaga, Oktay; Yoon, Euisik; Kim, Hak-Sung. 2006. "Aspartate Aminotransferase (AST/GOT) and Alanine Aminotransferase (ALT/GPT) Detection Techniques." Sensors 6, no. 7: 756-782.

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