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Nitric Oxide Detection with Glassy Carbon Electrodes Coated with Charge-different Polymer Films
Department of Chemistry, Faculty of Science, Kanazawa University, Kakuma, Kanazawa, Ishikawa 920-1192, Japan
* Author to whom correspondence should be addressed.
Received: 9 June 2004 / Accepted: 28 October 2004 / Published: 26 April 2005
Abstract: Trace amounts of nitric oxide (NO) have been determined in aqueous phosphate buffersolutions (pH=7.4) by using a glassy carbon electrode coated with three charge-different polymerfilms. The glassy carbon electrode was coated first with negatively charged Nafion film containingtetrakis(pentafluorophenylporphyrin) iron(III) chloride (Fe(III)TPFPP) as the NO oxidation catalyst,and then with positively charged poly(acrylamide-co-diallyldimethylammonium chloride) (PADDA)and with neutral poly(dimethylsiloxane) (silicone) at the outermost layer. This polymer-coatedelectrode showed an excellent selectivity towards NO against possible concomitants in blood such asnitrite, ascorbic acid, uric acid, and dopamine. All current ratios between each concomitant and NOat the cyclic voltammogram was in 10-3 ~ 10-4. This type of electrode showed a detection limit of80 nM for NO. It was speculated from the electrochemical study in methanol that high-valent oxoiron(IV) of Fe(TPFPP) participated in the catalytic oxidation of NO.
Keywords: polymer-coated electrode; nitric oxide detection; tetrakis(pentafluoro-phenylporphyrin)iron(III) chloride.
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MDPI and ACS Style
Ikeda, O.; Yoshinaga, K.; Lei, J. Nitric Oxide Detection with Glassy Carbon Electrodes Coated with Charge-different Polymer Films. Sensors 2005, 5, 161-170.
Ikeda O, Yoshinaga K, Lei J. Nitric Oxide Detection with Glassy Carbon Electrodes Coated with Charge-different Polymer Films. Sensors. 2005; 5(4):161-170.
Ikeda, Osamu; Yoshinaga, Kumiko; Lei, Jianping. 2005. "Nitric Oxide Detection with Glassy Carbon Electrodes Coated with Charge-different Polymer Films." Sensors 5, no. 4: 161-170.