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Sensors 2018, 18(2), 485; doi:10.3390/s18020485

VHH Antibodies: Reagents for Mycotoxin Detection in Food Products

College of Food Science and Technology, Huazhong Agricultural University, Wuhan 430070, China
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Received: 28 November 2017 / Revised: 28 January 2018 / Accepted: 2 February 2018 / Published: 6 February 2018
(This article belongs to the Section Biosensors)
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Abstract

Mycotoxins are the toxic secondary metabolites produced by fungi and they are a worldwide public health concern. A VHH antibody (or nanobody) is the smallest antigen binding entity and is produced by heavy chain only antibodies. Compared with conventional antibodies, VHH antibodies overcome many pitfalls typically encountered in clinical therapeutics and immunodiagnostics. Likewise, VHH antibodies are particularly useful for monitoring mycotoxins in food and feedstuffs, as they are easily genetic engineered and have superior stability. In this review, we summarize the efforts to produce anti-mycotoxins VHH antibodies and associated assays, presenting VHH as a potential tool in mycotoxin analysis. View Full-Text
Keywords: mycotoxin; VHH antibody; immunoassay mycotoxin; VHH antibody; immunoassay
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Wang, J.; Mukhtar, H.; Ma, L.; Pang, Q.; Wang, X. VHH Antibodies: Reagents for Mycotoxin Detection in Food Products. Sensors 2018, 18, 485.

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