Next Article in Journal
The Shock Pulse Index and Its Application in the Fault Diagnosis of Rolling Element Bearings
Previous Article in Journal
An Assessment of Iterative Reconstruction Methods for Sparse Ultrasound Imaging
Previous Article in Special Issue
Plasmonic Fiber Optic Refractometric Sensors: From Conventional Architectures to Recent Design Trends
Article Menu
Issue 3 (March) cover image

Export Article

Open AccessReview
Sensors 2017, 17(3), 540; doi:10.3390/s17030540

Label-Free Biological and Chemical Sensing Using Whispering Gallery Mode Optical Resonators: Past, Present, and Future

College of Optical Sciences, Department of Chemistry & Biochemistry, University of Arizona Cancer Center, University of Arizona, Tucson, AZ 85721, USA
Academic Editor: Alexandre François
Received: 3 October 2016 / Revised: 21 February 2017 / Accepted: 24 February 2017 / Published: 8 March 2017
(This article belongs to the Special Issue Label-Free Optical Biosensors)
View Full-Text   |   Download PDF [3052 KB, uploaded 8 March 2017]   |  

Abstract

Sensitive and rapid label-free biological and chemical sensors are needed for a wide variety of applications including early disease diagnosis and prognosis, the monitoring of food and water quality, as well as the detection of bacteria and viruses for public health concerns and chemical threat sensing. Whispering gallery mode optical resonator based sensing is a rapidly developing field due to the high sensitivity and speed of these devices as well as their label-free nature. Here, we describe the history of whispering gallery mode optical resonator sensors, the principles behind detection, the latest developments in the fields of biological and chemical sensing, current challenges toward widespread adoption of these devices, and an outlook for the future. In addition, we evaluate the performance capabilities of these sensors across three key parameters: sensitivity, selectivity, and speed. View Full-Text
Keywords: label-free; biosensing; chemical sensing; optical resonator; single molecule; microcavity; whispering gallery mode label-free; biosensing; chemical sensing; optical resonator; single molecule; microcavity; whispering gallery mode
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Su, J. Label-Free Biological and Chemical Sensing Using Whispering Gallery Mode Optical Resonators: Past, Present, and Future. Sensors 2017, 17, 540.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Sensors EISSN 1424-8220 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top