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Sensors 2017, 17(12), 2732; https://doi.org/10.3390/s17122732

Plasmonic Optical Fiber-Grating Immunosensing: A Review

1
Institute of Photonics Technology, Jinan University, Guangzhou 510632, China
2
Electromagnetism and Telecommunication Department, University of Mons, Boulevard Dolez 31, 7000 Mons, Belgium
*
Author to whom correspondence should be addressed.
Received: 4 October 2017 / Revised: 13 November 2017 / Accepted: 24 November 2017 / Published: 26 November 2017
(This article belongs to the Special Issue Surface Plasmon Resonance Sensing)
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Abstract

Plasmonic immunosensors are usually made of a noble metal (in the form of a film or nanoparticles) on which bioreceptors are grafted to sense analytes based on the antibody/antigen or other affinity mechanism. Optical fiber configurations are a miniaturized counterpart to the bulky Kretschmann prism and allow easy light injection and remote operation. To excite a surface plasmon (SP), the core-guided light is locally outcoupled. Unclad optical fibers were the first configurations reported to this end. Among the different architectures able to bring light in contact with the surrounding medium, a great quantity of research is today being conducted on metal-coated fiber gratings photo-imprinted in the fiber core, as they provide modal features that enable SP generation at any wavelength, especially in the telecommunication window. They are perfectly suited for use with cost-effective high-resolution interrogators, allowing both a high sensitivity and a low limit of detection to be reached in immunosensing. This paper will review recent progress made in this field with different kinds of gratings: uniform, tilted and eccentric short-period gratings as well as long-period fiber gratings. Practical cases will be reported, showing that such sensors can be used in very small volumes of analytes and even possibly applied to in vivo diagnosis. View Full-Text
Keywords: optical fibers; fiber Bragg gratings; plasmonics; sensing; nanoparticles optical fibers; fiber Bragg gratings; plasmonics; sensing; nanoparticles
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).
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Guo, T.; González-Vila, Á.; Loyez, M.; Caucheteur, C. Plasmonic Optical Fiber-Grating Immunosensing: A Review. Sensors 2017, 17, 2732.

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