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Sensors 2017, 17(1), 63; doi:10.3390/s17010063

Integration of Curved D-Type Optical Fiber Sensor with Microfluidic Chip

1
Department of Physics, Fu-Jen Catholic University, New Taipei City 24205, Taiwan
2
Graduate Institute of Applied Science and Engineering, Fu-Jen Catholic University, New Taipei City 24205, Taiwan
*
Author to whom correspondence should be addressed.
Academic Editor: Vittorio M. N. Passaro
Received: 22 November 2016 / Revised: 16 December 2016 / Accepted: 27 December 2016 / Published: 30 December 2016
(This article belongs to the Section Physical Sensors)
View Full-Text   |   Download PDF [3292 KB, uploaded 30 December 2016]   |  

Abstract

A curved D-type optical fiber sensor (OFS) combined with a microfluidic chip is proposed. This OFS, based on surface plasmon resonance (SPR) of the Kretchmann’s configuration, is applied as a biosensor to measure the concentrations of different bio-liquids such as ethanol, methanol, and glucose solutions. The SPR phenomenon is attained by using the optical fiber to guide the light source to reach the side-polished, gold-coated region. Integrating this OFS with a polymethylmethacrylate (PMMA)-based microfluidic chip, the SPR spectra for liquids with different refractive indices are recorded. Experimentally, the sensitivity of the current biosensor was calculated to be in the order of 10−5 RIU. This microfluidic chip-integrated OFS could be valuable for monitoring subtle changes in biological samples such as blood sugar, allergen, and biomolecular interactions. View Full-Text
Keywords: optical fiber sensor; surface plasmon resonance; biosensor; microfluidic chip optical fiber sensor; surface plasmon resonance; biosensor; microfluidic chip
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Sun, Y.-S.; Li, C.-J.; Hsu, J.-C. Integration of Curved D-Type Optical Fiber Sensor with Microfluidic Chip. Sensors 2017, 17, 63.

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