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Sensors 2016, 16(5), 598; doi:10.3390/s16050598

Enhanced Tissue Ablation Efficiency with a Mid-Infrared Nonlinear Frequency Conversion Laser System and Tissue Interaction Monitoring Using Optical Coherence Tomography

1
Beckman Laser Institute Korea, Dankook University, 119, Dandae-ro, Dongnam-gu, Cheonan-si, Chungnam 31116, Korea
2
Biomedical Engineering, College of Medicine, Dankook University, 119, Dandae-ro, Dongnam-gu, Cheonan-si, Chungnam 31116, Korea
*
Author to whom correspondence should be addressed.
Academic Editor: Vittorio M. N. Passaro
Received: 22 February 2016 / Revised: 8 April 2016 / Accepted: 21 April 2016 / Published: 26 April 2016
(This article belongs to the Section Physical Sensors)
View Full-Text   |   Download PDF [2400 KB, uploaded 26 April 2016]   |  

Abstract

We report development of optical parametric oscillator (OPO)-based mid-infrared laser system that utilizes a periodically poled nonlinear crystal pumped by a near-infrared (NIR) laser. We obtained a mid-infrared average output of 8 W at an injection current of 20 A from a quasi-phase-matched OPO using an external cavity configuration. Laser tissue ablation efficiency is substantially affected by several parameters, including an optical fluence rate, wavelength of the laser source, and the optical properties of target tissue. Dimensions of wavelength and radiant exposure dependent tissue ablation are quantified using Fourier domain optical coherence tomography and the ablation efficiency was compared to a non-converted NIR laser system. View Full-Text
Keywords: near-infrared laser; mid-infrared laser system; optical coherence tomography; optical parametric oscillator; tissue ablation efficiency near-infrared laser; mid-infrared laser system; optical coherence tomography; optical parametric oscillator; tissue ablation efficiency
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Kim, B.; Kim, D.Y. Enhanced Tissue Ablation Efficiency with a Mid-Infrared Nonlinear Frequency Conversion Laser System and Tissue Interaction Monitoring Using Optical Coherence Tomography. Sensors 2016, 16, 598.

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