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Sensors 2015, 15(2), 3801-3829; doi:10.3390/s150203801

Electrochemical DNA Hybridization Sensors Based on Conducting Polymers

1
Nanotechnology Research Center and Department of Applied Life Science, College of Biomedical and Health Science, Konkuk University, Chungju 380-701, Korea
2
Center for Advanced Instrumentation, Korea Research Institute of Standards and Science (KRISS), Daejeon 305-340, Korea
*
Author to whom correspondence should be addressed.
Received: 29 October 2014 / Accepted: 27 January 2015 / Published: 5 February 2015
(This article belongs to the Special Issue Amperometric Biosensors)
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Abstract

Conducting polymers (CPs) are a group of polymeric materials that have attracted considerable attention because of their unique electronic, chemical, and biochemical properties. This is reflected in their use in a wide range of potential applications, including light-emitting diodes, anti-static coating, electrochromic materials, solar cells, chemical sensors, biosensors, and drug-release systems. Electrochemical DNA sensors based on CPs can be used in numerous areas related to human health. This review summarizes the recent progress made in the development and use of CP-based electrochemical DNA hybridization sensors. We discuss the distinct properties of CPs with respect to their use in the immobilization of probe DNA on electrode surfaces, and we describe the immobilization techniques used for developing DNA hybridization sensors together with the various transduction methods employed. In the concluding part of this review, we present some of the challenges faced in the use of CP-based DNA hybridization sensors, as well as a future perspective. View Full-Text
Keywords: electrochemical DNA sensors; conducting polymers; immobilization techniques; transduction mechanism electrochemical DNA sensors; conducting polymers; immobilization techniques; transduction mechanism
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Rahman, M.M.; Li, X.-B.; Lopa, N.S.; Ahn, S.J.; Lee, J.-J. Electrochemical DNA Hybridization Sensors Based on Conducting Polymers. Sensors 2015, 15, 3801-3829.

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