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Sensors 2014, 14(5), 8940-8949; doi:10.3390/s140508940
Article

Unusual Multiple Production of N-Acylhomoserine Lactones a by Burkholderia sp. Strain C10B Isolated from Dentine Caries

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Received: 18 April 2014; in revised form: 4 May 2014 / Accepted: 13 May 2014 / Published: 21 May 2014
(This article belongs to the Section Biosensors)
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Abstract: Bacteria realize the ability to communicate by production of quorum sensing (QS) molecules called autoinducers, which regulate the physiological activities in their ecological niches. The oral cavity could be a potential area for the presence of QS bacteria. In this study, we report the isolation of a QS bacterial isolate C10B from dentine caries. Preliminary screening using Chromobacterium violaceum CV026 biosensor showed that isolate C10B was able to produce N-acylhomoserine lactones (AHLs). This bacterium was further identified as a member of Burkholderia, an opportunistic pathogen. The isolated Burkholderia sp. was confirmed to produce N-hexanoyl-L-homoserine lactone (C6-HSL), N-octanoyl-L-homoserine lactone (C8-HSL), N-decanoyl-L-homoserine lactone (C10-HSL) and N-dodecanoyl-L-homoserine lactone (C12-HSL).
Keywords: Chromobacterium violaceum CV026; N-hexanoyl-L-homoserine lactone (C6-HSL); N-octanoyl-L-homoserine lactone (C8-HSL); N-decanoyl-L-homoserine lactone (C10-HSL); N-dodecanoyl-L-homoserine lactone (C12-HSL); oral cavity; dentine caries; quorum sensing (QS) Chromobacterium violaceum CV026; N-hexanoyl-L-homoserine lactone (C6-HSL); N-octanoyl-L-homoserine lactone (C8-HSL); N-decanoyl-L-homoserine lactone (C10-HSL); N-dodecanoyl-L-homoserine lactone (C12-HSL); oral cavity; dentine caries; quorum sensing (QS)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Goh, S.Y.; Tan, W.-S.; Khan, S.A.; Chew, H.P.; Kasim, N.H.A.; Yin, W.-F.; Chan, K.-G. Unusual Multiple Production of N-Acylhomoserine Lactones a by Burkholderia sp. Strain C10B Isolated from Dentine Caries. Sensors 2014, 14, 8940-8949.

AMA Style

Goh SY, Tan W-S, Khan SA, Chew HP, Kasim NHA, Yin W-F, Chan K-G. Unusual Multiple Production of N-Acylhomoserine Lactones a by Burkholderia sp. Strain C10B Isolated from Dentine Caries. Sensors. 2014; 14(5):8940-8949.

Chicago/Turabian Style

Goh, Share Y.; Tan, Wen-Si; Khan, Saad A.; Chew, Hooi P.; Kasim, Noor H.A.; Yin, Wai-Fong; Chan, Kok-Gan. 2014. "Unusual Multiple Production of N-Acylhomoserine Lactones a by Burkholderia sp. Strain C10B Isolated from Dentine Caries." Sensors 14, no. 5: 8940-8949.



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