Next Article in Journal
Nanosized Thin SnO2 Layers Doped with Te and TeO2 as Room Temperature Humidity Sensors
Previous Article in Journal
Electrochemical Detection of p-Aminophenol by Flexible Devices Based on Multi-Wall Carbon Nanotubes Dispersed in Electrochemically Modified Nafion
Article Menu

Export Article

Open AccessArticle
Sensors 2014, 14(5), 8940-8949; doi:10.3390/s140508940

Unusual Multiple Production of N-Acylhomoserine Lactones a by Burkholderia sp. Strain C10B Isolated from Dentine Caries

1
Division of Genetics and Molecular Biology, Institute of Biological Sciences, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia
2
Department of Restorative Dentistry, Faculty of Dentistry, University of Malaya, 50603 Kuala Lumpur, Malaysia
*
Author to whom correspondence should be addressed.
Received: 18 April 2014 / Revised: 4 May 2014 / Accepted: 13 May 2014 / Published: 21 May 2014
(This article belongs to the Section Biosensors)
View Full-Text   |   Download PDF [301 KB, uploaded 21 June 2014]   |  

Abstract

Bacteria realize the ability to communicate by production of quorum sensing (QS) molecules called autoinducers, which regulate the physiological activities in their ecological niches. The oral cavity could be a potential area for the presence of QS bacteria. In this study, we report the isolation of a QS bacterial isolate C10B from dentine caries. Preliminary screening using Chromobacterium violaceum CV026 biosensor showed that isolate C10B was able to produce N-acylhomoserine lactones (AHLs). This bacterium was further identified as a member of Burkholderia, an opportunistic pathogen. The isolated Burkholderia sp. was confirmed to produce N-hexanoyl-L-homoserine lactone (C6-HSL), N-octanoyl-L-homoserine lactone (C8-HSL), N-decanoyl-L-homoserine lactone (C10-HSL) and N-dodecanoyl-L-homoserine lactone (C12-HSL).
Keywords: Chromobacterium violaceum CV026; N-hexanoyl-L-homoserine lactone (C6-HSL); N-octanoyl-L-homoserine lactone (C8-HSL); N-decanoyl-L-homoserine lactone (C10-HSL); N-dodecanoyl-L-homoserine lactone (C12-HSL); oral cavity; dentine caries; quorum sensing (QS) Chromobacterium violaceum CV026; N-hexanoyl-L-homoserine lactone (C6-HSL); N-octanoyl-L-homoserine lactone (C8-HSL); N-decanoyl-L-homoserine lactone (C10-HSL); N-dodecanoyl-L-homoserine lactone (C12-HSL); oral cavity; dentine caries; quorum sensing (QS)
Figures

This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Goh, S.Y.; Tan, W.-S.; Khan, S.A.; Chew, H.P.; Kasim, N.H.A.; Yin, W.-F.; Chan, K.-G. Unusual Multiple Production of N-Acylhomoserine Lactones a by Burkholderia sp. Strain C10B Isolated from Dentine Caries. Sensors 2014, 14, 8940-8949.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Sensors EISSN 1424-8220 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top