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Sensors 2014, 14(4), 6965-6976; doi:10.3390/s140406965

Response of a New Low-Coherence Fabry-Perot Sensor to Hematocrit Levels in Human Blood

Faculty of Electronics, Telecommunications and Informatics, Department of Metrology and Optoelectronics, Gdańsk University of Technology, 11/12 Narutowicza Street, Gdańsk 80-233, Poland
Received: 6 February 2014 / Revised: 8 April 2014 / Accepted: 10 April 2014 / Published: 21 April 2014
(This article belongs to the Section Biosensors)
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Abstract

In this paper, a low-coherence Fabry-Perot sensor with a spectrally measured signal processing response to the refractive index of liquids is presented. Optical fiber sensors are potentially capable of continuous measuring hematocrit levels in blood. Low-coherence Fabry-Perot interferometric sensors offer a robust solution, where information about the measurand is encoded in the full spectrum of light reflected from the sensing interferometer. The first step in the research on such sensor is the assessment of its performance under favorable conditions, i.e., using blood samples from healthy volunteers tested in vitro. Such an experiment was conducted using a sensor comprising a superluminescent diode source, an optical spectrum analyzer working as the detection setup and a sensing Fabry-Perot interferometer providing high interference contrast. The response of this sensor was recorded for several samples and compared with the reference laboratory method. The coefficient of determination (R2) for a linear relationship between the results given by both methods was 0.978 and the difference between these results was less than 1%. The presented results suggest that further research into the performance of the sensor is merited. View Full-Text
Keywords: low-coherence interferometer; Fabry-Perot interferometer; fiber optic sensors; hematocrit low-coherence interferometer; Fabry-Perot interferometer; fiber optic sensors; hematocrit
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Jędrzejewska-Szczerska, M. Response of a New Low-Coherence Fabry-Perot Sensor to Hematocrit Levels in Human Blood. Sensors 2014, 14, 6965-6976.

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