Dual-Frequency Piezoelectric Transducers for Contrast Enhanced Ultrasound Imaging
AbstractFor many years, ultrasound has provided clinicians with an affordable and effective imaging tool for applications ranging from cardiology to obstetrics. Development of microbubble contrast agents over the past several decades has enabled ultrasound to distinguish between blood flow and surrounding tissue. Current clinical practices using microbubble contrast agents rely heavily on user training to evaluate degree of localized perfusion. Advances in separating the signals produced from contrast agents versus surrounding tissue backscatter provide unique opportunities for specialized sensors designed to image microbubbles with higher signal to noise and resolution than previously possible. In this review article, we describe the background principles and recent developments of ultrasound transducer technology for receiving signals produced by contrast agents while rejecting signals arising from soft tissue. This approach relies on transmitting at a low-frequency and receiving microbubble harmonic signals at frequencies many times higher than the transmitted frequency. Design and fabrication of dual-frequency transducers and the extension of recent developments in transducer technology for dual-frequency harmonic imaging are discussed. View Full-Text
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Martin, K.H.; Lindsey, B.D.; Ma, J.; Lee, M.; Li, S.; Foster, F.S.; Jiang, X.; Dayton, P.A. Dual-Frequency Piezoelectric Transducers for Contrast Enhanced Ultrasound Imaging. Sensors 2014, 14, 20825-20842.
Martin KH, Lindsey BD, Ma J, Lee M, Li S, Foster FS, Jiang X, Dayton PA. Dual-Frequency Piezoelectric Transducers for Contrast Enhanced Ultrasound Imaging. Sensors. 2014; 14(11):20825-20842.Chicago/Turabian Style
Martin, K. H.; Lindsey, Brooks D.; Ma, Jianguo; Lee, Mike; Li, Sibo; Foster, F. S.; Jiang, Xiaoning; Dayton, Paul A. 2014. "Dual-Frequency Piezoelectric Transducers for Contrast Enhanced Ultrasound Imaging." Sensors 14, no. 11: 20825-20842.