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Opening up the Window into “Chemobrain”: A Neuroimaging Review
AbstractAs more chemotherapy-treated cancer patients are reaching survivorship, side-effects such as cognitive impairment warrant research attention. The advent of neuroimaging has helped uncover a neural basis for these deficits. This paper offers a review of neuroimaging investigations in chemotherapy-treated adult cancer patients, discussing the benefits and limitations of each technique and study design. Additionally, despite the assumption given by the chemobrain label that chemotherapy is the only causative agent of these deficits, other factors will be considered. Suggestions are made on how to more comprehensively study these cognitive changes using imaging techniques, thereby promoting generalizability of the results to clinical applications. Continued investigations may yield better long-term quality of life outcomes by supporting patients’ self-reports, and revealing brain regions being affected by chemotherapy.
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Scherling, C.S.; Smith, A. Opening up the Window into “Chemobrain”: A Neuroimaging Review. Sensors 2013, 13, 3169-3203.View more citation formats
Scherling CS, Smith A. Opening up the Window into “Chemobrain”: A Neuroimaging Review. Sensors. 2013; 13(3):3169-3203.Chicago/Turabian Style
Scherling, Carole S.; Smith, Andra. 2013. "Opening up the Window into “Chemobrain”: A Neuroimaging Review." Sensors 13, no. 3: 3169-3203.