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Sensors 2012, 12(7), 9791-9799; doi:10.3390/s120709791
Article

Sensitivity of a Label-Free Guided-Mode Resonant Optical Biosensor with Different Modes

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Received: 4 June 2012; in revised form: 26 June 2012 / Accepted: 2 July 2012 / Published: 18 July 2012
(This article belongs to the Section Biosensors)
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Abstract: Sensitivity is a key factor in the performance of a sensor. To achieve maximum guided-mode resonant optical biosensor sensitivity, a comparison of biosensor sensitivity for Transverse Electric (TE) and Transverse Magnetic (TM) modes based on the distribution of electric fields is presented in this article. A label-free guided-mode resonant optical biosensor is designed using the quarter-wave anti-reflection method to reflect only a narrow band of wavelengths modulated by the adsorption of a biochemical material on the sensor surface at the reflected frequency. With the distribution of electric fields simulated according to the Rigorous Coupled Wave Analysis (RCWA) theory, it is found that the full width at half maximum of the TM mode is (~4 nm) narrower than that of the TE mode (~20 nm), and the surface sensitivity of the TE mode incident light is three times that of the TM mode. It is proposed in this article that the light mode plays an important role in the sensitivity of guided-mode resonant biosensors.
Keywords: sensitivity; biosensor; TE mode; TM mode; guided mode resonance (GMRF) sensitivity; biosensor; TE mode; TM mode; guided mode resonance (GMRF)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Wang, Q.; Zhang, D.; Yang, H.; Tao, C.; Huang, Y.; Zhuang, S.; Mei, T. Sensitivity of a Label-Free Guided-Mode Resonant Optical Biosensor with Different Modes. Sensors 2012, 12, 9791-9799.

AMA Style

Wang Q, Zhang D, Yang H, Tao C, Huang Y, Zhuang S, Mei T. Sensitivity of a Label-Free Guided-Mode Resonant Optical Biosensor with Different Modes. Sensors. 2012; 12(7):9791-9799.

Chicago/Turabian Style

Wang, Qi; Zhang, Dawei; Yang, Huiyin; Tao, Chunxian; Huang, Yuanshen; Zhuang, Songlin; Mei, Ting. 2012. "Sensitivity of a Label-Free Guided-Mode Resonant Optical Biosensor with Different Modes." Sensors 12, no. 7: 9791-9799.


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