Sensors 2012, 12(5), 6645-6665; doi:10.3390/s120506645
Review

Detection of AI-2 Receptors in Genomes of Enterobacteriaceae Suggests a Role of Type-2 Quorum Sensing in Closed Ecosystems

Plant Protection Division, Agroscope Changins-W├Ądenswil ACW, Schloss 1, W├Ądenswil CH-8820, Switzerland
* Author to whom correspondence should be addressed.
Received: 31 March 2012; in revised form: 11 May 2012 / Accepted: 16 May 2012 / Published: 21 May 2012
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Abstract: The LuxS enzyme, an S-ribosyl-homocysteine lyase, catalyzes the production of the signal precursor for autoinducer-2 mediated quorum sensing (QS-2) in Vibrio. Its widespread occurrence among bacteria is often considered the evidence for a universal language for interspecies communication. Presence of the luxS gene and production of the autoinducer-2 (AI-2) signal have repeatedly been the only evidences presented to assign a functional QS-2 to the most diverse species. In fact, LuxS has a primary metabolic role as part of the activated methyl cycle. In this review we have analyzed the distribution of QS-2 related genes in Enterobacteriaceae by moving the focus of the investigation from AI-2 production to the detection of potential AI-2 receptors. The latter are common in pathogens or endosymbionts of animals, but were also found in a limited number of Enterobacteriaceae of the genera Enterobacter, Klebsiella, and Pantoea that live in close association with plants or fungi. Although a precise function of QS-2 in these species has not been identified, they all show an endophytic or endosymbiontic lifestyle that suggests a role of type-2 quorum sensing in the adaptation to closed ecosystems.
Keywords: LuxS; N-acyl homoserine lactone; Erwinia; Pantoea; Salmonella; Serratia; Enterobacter; metabolism; autoinducer; plant pathogen; nitrogen fixation

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MDPI and ACS Style

Rezzonico, F.; Smits, T.H.M.; Duffy, B. Detection of AI-2 Receptors in Genomes of Enterobacteriaceae Suggests a Role of Type-2 Quorum Sensing in Closed Ecosystems. Sensors 2012, 12, 6645-6665.

AMA Style

Rezzonico F, Smits THM, Duffy B. Detection of AI-2 Receptors in Genomes of Enterobacteriaceae Suggests a Role of Type-2 Quorum Sensing in Closed Ecosystems. Sensors. 2012; 12(5):6645-6665.

Chicago/Turabian Style

Rezzonico, Fabio; Smits, Theo H. M.; Duffy, Brion. 2012. "Detection of AI-2 Receptors in Genomes of Enterobacteriaceae Suggests a Role of Type-2 Quorum Sensing in Closed Ecosystems." Sensors 12, no. 5: 6645-6665.

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