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Sensors 2012, 12(3), 2519-2538; doi:10.3390/s120302519

Quorum Sensing and Bacterial Social Interactions in Biofilms

1,2,*  and 2
1 Department of Microbiology and Immunology, Dalhousie University, Halifax, NS B3H 1W2, Canada 2 Department of Applied Oral Sciences, Dalhousie University, Halifax, NS, B3H 1W2, Canada
* Author to whom correspondence should be addressed.
Received: 6 January 2012 / Revised: 9 February 2012 / Accepted: 10 February 2012 / Published: 23 February 2012
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Many bacteria are known to regulate their cooperative activities and physiological processes through a mechanism called quorum sensing (QS), in which bacterial cells communicate with each other by releasing, sensing and responding to small diffusible signal molecules. The ability of bacteria to communicate and behave as a group for social interactions like a multi-cellular organism has provided significant benefits to bacteria in host colonization, formation of biofilms, defense against competitors, and adaptation to changing environments. Importantly, many QS-controlled activities have been involved in the virulence and pathogenic potential of bacteria. Therefore, understanding the molecular details of quorum sensing mechanisms and their controlled social activities may open a new avenue for controlling bacterial infections.
Keywords: quorum sensing; biofilms; bacterial social interactions; bacterial infections quorum sensing; biofilms; bacterial social interactions; bacterial infections
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Li, Y.-H.; Tian, X. Quorum Sensing and Bacterial Social Interactions in Biofilms. Sensors 2012, 12, 2519-2538.

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