Next Article in Journal
Previous Article in Journal
Sensors 2011, 11(9), 8769-8781; doi:10.3390/s110908769
Article

Gamma-Ray Sterilization Effects in Silica Nanoparticles/γ-APTES Nanocomposite-Based pH-Sensitive Polysilicon Wire Sensors

1,*  and 2
Received: 13 August 2011; in revised form: 7 September 2011 / Accepted: 8 September 2011 / Published: 13 September 2011
(This article belongs to the Section Physical Sensors)
View Full-Text   |   Download PDF [1904 KB, uploaded 21 June 2014]
Abstract: In this paper, we report the γ-ray sterilization effects in pH-sensitive polysilicon wire (PSW) sensors using a mixture of 3-aminopropyltriethoxysilane (γ-APTES) and polydimethylsiloxane (PDMS)-treated hydrophobic fumed silica nanoparticles (NPs) as a sensing membrane. pH analyses showed that the γ-ray irradiation-induced sensitivity degradation of the PSW pH sensor covered with γ-APTES/silica NPs nanocomposite (γ-APTES+NPs) could be restored to a condition even better than prior to γ-ray irradiation by 40-min of post-sterilization room-temperature UV annealing. We found that the trapping charges caused by γ-ray sterilization primarily concentrated in the native oxide layer for the pH sensor covered with γ-APTES, but accumulated in the γ-APTES+NPs layer for the γ-APTES+NPs-covered sensor. It is believed that mixing the PDMS-treated silica NPs into g-APTES provides many g-APTES/SiO2 interfaces for the accumulation of trapping charges and for post-sterilization UV oxidation, thus restoring γ-ray-induced sensor degradation. The PDMS-treated silica NPs not only enhance the sensitivity of the pH-sensitive PSW sensors but are also able to withstand the two-step sterilization resulting from γ-ray and UV irradiations. This investigation suggests γ-ray irradiation could be used as a highly-efficient sterilization method for γ-APTES-based pH-sensitive biosensors.
Keywords: 3-aminopropyltriethoxysilane; polydimethylsiloxane; silica nanoparticles; γ-ray sterilization; post-sterilization UV annealing 3-aminopropyltriethoxysilane; polydimethylsiloxane; silica nanoparticles; γ-ray sterilization; post-sterilization UV annealing
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Export to BibTeX |
EndNote


MDPI and ACS Style

Lin, J.-J.; Hsu, P.-Y. Gamma-Ray Sterilization Effects in Silica Nanoparticles/γ-APTES Nanocomposite-Based pH-Sensitive Polysilicon Wire Sensors. Sensors 2011, 11, 8769-8781.

AMA Style

Lin J-J, Hsu P-Y. Gamma-Ray Sterilization Effects in Silica Nanoparticles/γ-APTES Nanocomposite-Based pH-Sensitive Polysilicon Wire Sensors. Sensors. 2011; 11(9):8769-8781.

Chicago/Turabian Style

Lin, Jing-Jenn; Hsu, Po-Yen. 2011. "Gamma-Ray Sterilization Effects in Silica Nanoparticles/γ-APTES Nanocomposite-Based pH-Sensitive Polysilicon Wire Sensors." Sensors 11, no. 9: 8769-8781.


Sensors EISSN 1424-8220 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert