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A Parkinson’s Disease Measurement System Using Laser Lines and a CMOS Image Sensor
Department of Optics and Photonics, National Central University, 300 Chung-Da Rd., Chung-Li 32001, Taiwan
The Institute of Traditional Medicine, National Yang-Ming University, Taipei, Taiwan
Center for Traditional Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
Department of Biomedical Imaging & Radiological Sciences, National Yang-Ming University, Taipei, Taiwan
* Author to whom correspondence should be addressed.
Received: 8 December 2010; in revised form: 13 January 2011 / Accepted: 17 January 2011 / Published: 26 January 2011
Abstract: This paper presents a non-invasive, non-contact system for the measurement of the arterial dorsum manus vibration waveforms of Parkinson disease patients. The laser line method is applied to detect the dorsum manus vibration in rest and postural situations. The proposed measurement system mainly consists of a laser diode and a low cost complementary metal-oxide semiconductor (CMOS) image sensor. Laser line and centroid methods are combined with the Fast Fourier Transform (FFT) in this study. The shape and frequency and relative frequency of the dorsum manus vibration waveforms can be detected rapidly using our Parkinson’s disease measurement system. A laser line near the wrist joint is used as the testing line. The experimental results show an obvious increase in the amplitude and frequency of dorsum manus variation in the measured region in patients suffering from Parkinson’s disease, indicating the obvious effects of the disease. Both in postural and rest state measurements, as the patient disease age increases the vibration frequency increases. The measurement system is well suited for evaluating and pre-diagnosing early stage Parkinson’s disease.
Keywords: Parkinson’s disease; laser triangulation measurement; centroid method; CMOS image sensor; Fast Fourier Transform (FFT)
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Chang, R.-S.; Chiu, J.-H.; Chen, F.-P.; Chen, J.-C.; Yang, J.-L. A Parkinson’s Disease Measurement System Using Laser Lines and a CMOS Image Sensor. Sensors 2011, 11, 1461-1475.
Chang R-S, Chiu J-H, Chen F-P, Chen J-C, Yang J-L. A Parkinson’s Disease Measurement System Using Laser Lines and a CMOS Image Sensor. Sensors. 2011; 11(2):1461-1475.
Chang, Rong-Seng; Chiu, Jen-Hwey; Chen, Fang-Pey; Chen, Jyh-Cheng; Yang, Jen-Lin. 2011. "A Parkinson’s Disease Measurement System Using Laser Lines and a CMOS Image Sensor." Sensors 11, no. 2: 1461-1475.