Sensors 2010, 10(5), 5063-5073; doi:10.3390/s100505063
Article

Novel Microwave-Assisted Synthesis of Poly(D,L-lactide): The Influence of Monomer/Initiator Molar Ratio on the Product Properties

1,* email, 2email, 3email, 1email, 3email and 1email
Received: 29 March 2010; in revised form: 26 April 2010 / Accepted: 28 April 2010 / Published: 20 May 2010
(This article belongs to the Section Physical Sensors)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Poly(D,L-lactide) synthesis using tin(II) 2-ethylhexanoate initiated ring-opening polymerization (ROP) takes over 30 hours in bulk at 120 °C. The use of microwave makes the same bulk polymerization process with the same initiator much faster and energy saving, with a reaction time of about 30 minutes at 100 °C. Here, the poly(lactide) synthesis was done in a microwave reactor, using frequency of 2.45 GHz and maximal power of 150 W. The reaction temperature was controlled via infra-red system for in-bulk-measuring, and was maintained at 100 °C. Different molar ratios of monomer and initiator, [M]/[I], of 1,000, 5,000 and 10,000 were used. The achieved average molar masses for the obtained polymers (determined by gel permeation chromatography) were in the interval from 26,700 to 112,500 g/mol. The polydispersion index was from 2.436 to 3.425. For applicative purposes, the obtained material was purified during the procedure of microsphere preparation. Microspheres were obtained by spraying a fine fog of polymer (D,L-lactide) solution in tetrahydrofuran into the water solution of poly(vinyl alcohol) with intensive stirring.
Keywords: poly(D,L-lactide); novel microwave synthesis; ring-opening polymerization (ROP)
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MDPI and ACS Style

Nikolic, L.; Ristic, I.; Adnadjevic, B.; Nikolic, V.; Jovanovic, J.; Stankovic, M. Novel Microwave-Assisted Synthesis of Poly(D,L-lactide): The Influence of Monomer/Initiator Molar Ratio on the Product Properties. Sensors 2010, 10, 5063-5073.

AMA Style

Nikolic L, Ristic I, Adnadjevic B, Nikolic V, Jovanovic J, Stankovic M. Novel Microwave-Assisted Synthesis of Poly(D,L-lactide): The Influence of Monomer/Initiator Molar Ratio on the Product Properties. Sensors. 2010; 10(5):5063-5073.

Chicago/Turabian Style

Nikolic, Ljubisa; Ristic, Ivan; Adnadjevic, Borivoj; Nikolic, Vesna; Jovanovic, Jelena; Stankovic, Mihajlo. 2010. "Novel Microwave-Assisted Synthesis of Poly(D,L-lactide): The Influence of Monomer/Initiator Molar Ratio on the Product Properties." Sensors 10, no. 5: 5063-5073.

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