Direct Electrochemistry and Electrocatalysis of Hemoglobin at Mesoporous Carbon Modified Electrode

doi:10.3390/s100201279

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Sensors 2010, 10(2), 1279-1290; doi:10.3390/s100201279

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Direct Electrochemistry and Electrocatalysis of Hemoglobin at Mesoporous Carbon Modified Electrode

Supeng Pei ¹ , Song Qu ²^,* and Yongming Zhang ¹^,*

¹ School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, Shanghai 200240, China ² College of Science, University of Shanghai for Science and Technology, Shanghai 200093, ChinaCollege of Science, University of Shanghai for Science and Technology, Shanghai 200093, China

* Authors to whom correspondence should be addressed.

Received: 30 November 2009; in revised form: 30 December 2009 / Accepted: 18 January 2010 / Published: 3 February 2010

(This article belongs to the Section Biosensors)

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Abstract: The novel highly ordered mesoporous carbon (known as FDU-15), prepared by the organic-organic self-assembly method was been used for first time for the immobilization of hemoglobin (Hb) and its bioelectrochemical properties were studied. The resulting Hb/FDU-15 film provided a favorable microenvironment for Hb to perform direct electron transfers at the electrode. The immobilized Hb also displayed its good electrocatalytic activity for the reduction of hydrogen peroxide. The results demonstrate that mesoporous carbon FDU-15 can improve the Hb loading with retention of its bioactivity and greatly promote the direct electron transfer, which can be attributed to its high specific surface area, uniform ordered porous structure, suitable pore size and biocompatibility. Our present study may provide an alternative way for the construction of nanostructure biofunctional surfaces and pave the way for its application to biosensors.

Keywords: hemoglobin; mesoporous carbon; direct electron transfer

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Cite This Article

MDPI and ACS Style

Pei, S.; Qu, S.; Zhang, Y. Direct Electrochemistry and Electrocatalysis of Hemoglobin at Mesoporous Carbon Modified Electrode. Sensors 2010, 10, 1279-1290.

AMA Style

Pei S., Qu S., Zhang Y. Direct Electrochemistry and Electrocatalysis of Hemoglobin at Mesoporous Carbon Modified Electrode. Sensors. 2010; 10(2):1279-1290.

Chicago/Turabian Style

Pei, Supeng; Qu, Song; Zhang, Yongming. 2010. "Direct Electrochemistry and Electrocatalysis of Hemoglobin at Mesoporous Carbon Modified Electrode." Sensors 10, no. 2: 1279-1290.

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