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Molbank 2017, 2017(1), M925; doi:10.3390/M925

Ethyl({[acryloyl(furan-2-ylmethyl)amino]acetyl}amino)acetate

1
Centre of Polymer Systems, University Institute, Tomas Bata University in Zlin, Tř. T. Bati 5678, 760 01, Zlin, Czech Republic
2
Biological Nanostructures Facility, Molecular Foundry, Lawrence Berkeley National Laboratory1 Cyclotron Rd., Berkeley, CA 94720, USA
*
Author to whom correspondence should be addressed.
Academic Editor: Norbert Haider
Received: 21 September 2016 / Revised: 26 December 2016 / Accepted: 4 January 2017 / Published: 9 January 2017
(This article belongs to the Section Organic Synthesis)
View Full-Text   |   Download PDF [1328 KB, uploaded 9 January 2017]   |  

Abstract

Ethyl({[acryloyl(furan-2-ylmethyl)amino]acetyl}amino)acetate was synthesized via Ugi four component (4C) reaction at ambient temperature. The protocol employs a reaction between formaldehyde, furfurylamine, acrylic acid, and ethyl 2-isocyanoacetate. The course of the reaction was found to be high yielding, and the resulting glycine ester derivative was well characterized by elemental analysis, FTIR, NMR spectroscopy, and mass spectrometric techniques. View Full-Text
Keywords: FTIR; NMR; peptides; peptoids; Ugi reaction FTIR; NMR; peptides; peptoids; Ugi reaction
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Ganesh, S.D.; Saha, N.; Zuckermann, R.N.; Sáha, P. Ethyl({[acryloyl(furan-2-ylmethyl)amino]acetyl}amino)acetate. Molbank 2017, 2017, M925.

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