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Molbank 2014, 2014(3), M833; doi:10.3390/M833
Short Note

N2-tert-Butoxycarbonyl-N5-[N-(9-fluorenylmethyloxycarbonyl)-2-aminoethyl]-(S)-2,5-diaminopentanoic Acid

*  and *
Department of Biosciences and Nutrition, Karolinska Institute (KI), Novum, Huddinge SE-141 83, Sweden
* Authors to whom correspondence should be addressed.
Received: 3 April 2014 / Accepted: 7 August 2014 / Published: 22 August 2014
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Abstract

N2-tert-Butoxycarbonyl-N5-[N-(9-fluorenylmethyloxycarbonyl)-2-aminoethyl]-(S)-2,5-diaminopentanoic acid (5) has been synthesized by the reaction of N2-tert-butoxycarbonyl-L-2,5-diaminopentanoic acid (Boc-L-ornithine, 3) and N-Fmoc-2-aminoacetaldehyde (N-Fmoc-glycinal, 4) in the presence of sodium cyanoborohydride in methanol containing 1% acetic acid at room temperature.
Keywords: reductive amination; N2-tert-butoxycarbonyl-N5-[N-(9-fluorenylmethyloxycarbonyl)- 2-aminoethyl]-(S)-2,5-diaminopentanoic acid; δN-(2-aminoethyl)-L-ornithine reductive amination; N2-tert-butoxycarbonyl-N5-[N-(9-fluorenylmethyloxycarbonyl)- 2-aminoethyl]-(S)-2,5-diaminopentanoic acid; δN-(2-aminoethyl)-L-ornithine
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Maity, J.; Stromberg, R. N2-tert-Butoxycarbonyl-N5-[N-(9-fluorenylmethyloxycarbonyl)-2-aminoethyl]-(S)-2,5-diaminopentanoic Acid. Molbank 2014, 2014, M833.

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