Molbank 2014, 2014(3), M832; doi:10.3390/M832
Short Note

Chitooligosaccharide-2,5-anhydro-D-mannonic Acid

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Received: 26 June 2014; Accepted: 14 August 2014 / Published: 19 August 2014
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Chitooligosaccharide with one 2,5-anhydro-D-mannofuranose unit at the reducing end (COSamf) was prepared by nitrous deamination of fully N-deacetylated chitosan. The oxidation of the amf-unit by chlorite sodium was achieved in high yield. The chemical structure of the targeted chitooligosaccharide-2,5-anhydro-D-mannonic acid with a degree of polymerization ~10 was fully characterized by NMR spectroscopy, MALDI-TOF mass spectrometry and size-exclusion chromatography. The success of this synthesis opens the way to a new generation of end-functionalized COS building blocks.
Keywords: chitosan; chitooligosaccharide-2,5-anhydro-D-mannofuranose; 2,5-anhydro-D-mannonic acid; nitrous deamination; oxidation
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MDPI and ACS Style

Salim, E.; Ailincai, D.; Trombotto, S. Chitooligosaccharide-2,5-anhydro-D-mannonic Acid. Molbank 2014, 2014, M832.

AMA Style

Salim E, Ailincai D, Trombotto S. Chitooligosaccharide-2,5-anhydro-D-mannonic Acid. Molbank. 2014; 2014(3):M832.

Chicago/Turabian Style

Salim, Emil; Ailincai, Daniela; Trombotto, Stéphane. 2014. "Chitooligosaccharide-2,5-anhydro-D-mannonic Acid." Molbank 2014, no. 3: M832.

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