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AbstractChitooligosaccharide with one 2,5-anhydro-D-mannofuranose unit at the reducing end (COSamf) was prepared by nitrous deamination of fully N-deacetylated chitosan. The oxidation of the amf-unit by chlorite sodium was achieved in high yield. The chemical structure of the targeted chitooligosaccharide-2,5-anhydro-D-mannonic acid with a degree of polymerization ~10 was fully characterized by NMR spectroscopy, MALDI-TOF mass spectrometry and size-exclusion chromatography. The success of this synthesis opens the way to a new generation of end-functionalized COS building blocks.
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Salim, E.; Ailincai, D.; Trombotto, S. Chitooligosaccharide-2,5-anhydro-D-mannonic Acid. Molbank 2014, 2014, M832.View more citation formats
Salim E, Ailincai D, Trombotto S. Chitooligosaccharide-2,5-anhydro-D-mannonic Acid. Molbank. 2014; 2014(3):M832.Chicago/Turabian Style
Salim, Emil; Ailincai, Daniela; Trombotto, Stéphane. 2014. "Chitooligosaccharide-2,5-anhydro-D-mannonic Acid." Molbank 2014, no. 3: M832.