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6-Chloro-2-hydroxy-2-trifluoromethyl-2H-chromene-3-carboxylic acid (5-allylsulfanyl-[1,3,4]thiadiazol-2-yl)-amide
Molbank 2014, 2014(3), M831; doi:10.3390/M831
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1,2,* , 1, 1,2, 3 and 4,5
1 School of Chemistry, University College of Science, University of Tehran, Tehran, 13145-143, Iran 2 Pharmaceutical and Cosmetic Research Center, University of Tehran Research Institute, (PCRC), Tehran, 14155-6455, Iran 3 Department of Medicinal Chemistry and Radiopharmacy, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, 14176, Iran 4 Department of Chemistry, University of Malaya, Kuala Lumpur, 50603, Malaysia 5 Chemistry Department, Faculty of Science, King Abdulaziz University, Jeddah 80203, Saudi Arabia
* Author to whom correspondence should be addressed.
Received: 15 April 2014 / Accepted: 17 July 2014 / Published: 6 August 2014
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Novel synthesis of a 2-amino-3-cyano-2,6-diphenyl pyridine by a one-pot multi-component reaction of 1,3-diphenylpropane-1,3-dione, malononitrile and phenethylamine in the presence of N-hydroxybenzamide and zinc chloride has been reported. The structure of the synthesized compound was assigned on the basis of its elemental analysis, 1H-NMR, 13C-NMR, IR and mass spectral data. X-ray structure analysis confirmed unambiguously the proposed structure. The photophysical properties (λAbs., λFlu.) in CH3OH, CH3CN, CH2Cl2 and the emission spectrum of the new compound in solution and in the solid state are reported.
Keywords: 2-amino-3-cyano-4,6-diarylpyridine; fluorescence; multi-component reaction; ZnCl2; N-hydroxybenzamide; malononitrile 2-amino-3-cyano-4,6-diarylpyridine; fluorescence; multi-component reaction; ZnCl2; N-hydroxybenzamide; malononitrile
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Zonouzi, A.; Izakian, Z.; Salehi, H.; Abdi, K.; Ng, S.W. 3-Cyano-4,6-diphenyl-2-(phenethylamino)pyridine. Molbank 2014, 2014, M831.

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