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Molbank 2009, 2009(3), M621; doi:10.3390/M621

Short Note

Synthesis of 4-[10H-Phenothiazin-10-yl(1H-tetrazol-5-yl)-methyl]phenol

Bathey R. Venkatraman ^1,* and Helen P. Kavitha ²

¹ Department of Chemistry, Periyar E.V.R. College, Tiruchirappalli-23, Tamil Nadu, India ² Department of Chemistry, SRM University, Ramapuram Campus, Chennai-89, Tamil Nadu, India

* Author to whom correspondence should be addressed.

Received: 3 September 2009 / Accepted: 21 September 2009 / Published: 22 September 2009

Download PDF Full-Text [23 KB, uploaded 22 September 2009 06:34 CET]

Abstract: This present work aims at synthesizing a novel tetrazole from phenothiazine. Phenothiazine is converted into a nitrile by reacting it with 4-hydroxybenzaldehyde, sodium metabisulphite and sodium cyanide. The nitrile on treatment with NaN₃/DMF yielded the corresponding tetrazole. The tetrazole obtained was characterized by IR, ¹H NMR, EI-MS and elemental analysis.

Keywords: 4-[10H-phenothiazin-10-yl(1H-tetrazol-5-yl)methyl]phenol; (4-hydroxyphenyl)(10H-phenothiazin-10-yl)acetonitrile

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  3D structure generated by CORINA by Molecular Networks.

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