Newly Synthesized Water Soluble Cholinium-Purpurin Photosensitizers and Their Stabilized Gold Nanoparticles as Promising Anticancer Agents

doi:10.3390/ijms9050864

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Int. J. Mol. Sci. 2008, 9(5), 864-871; doi:10.3390/ijms9050864

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Newly Synthesized Water Soluble Cholinium-Purpurin Photosensitizers and Their Stabilized Gold Nanoparticles as Promising Anticancer Agents

Dorjnamjin Demberelnyamba, Mama Ariunaa and Young K. Shim *

PDT Research Institute, School of Nano System Engineering, Inje University, Gimhae, Korea

* Author to whom correspondence should be addressed.

Received: 6 February 2008; in revised form: 15 May 2008 / Accepted: 19 May 2008 / Published: 23 May 2008

(This article belongs to the Special Issue Natural Compounds for Cancer Treatment and Prevention)

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Abstract: For possible future use in Photodynamic Therapy (PDT) and/or Photothermal Therapy (PTT) of cancer and screening of cancer cells a new type of ionic liquid photosensitizer –Cholinium-Purpurin-18 (Chol-Pu-18) – was synthesized and small gold (Au) nanoparticles, stabilized by this photosensitizer were prepared without adding any particular reducing agents and CTAB. UV-Vis spectroscopy and Transmission Electron Microscopy (TEM) were used for characterization of the nanoparticles and FAB-MS and NMR of the ionic liquid choline hydroxide, purpurin carboxylate and their ionic liquid type of photosensitizer were obtained.

Keywords: Ionic liquid type photosensitizers; choline; purpurin-18; cholinium-purpurin- 18; gold nanoparticles; anticancer agents

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MDPI and ACS Style

Demberelnyamba, D.; Ariunaa, M.; Shim, Y.K. Newly Synthesized Water Soluble Cholinium-Purpurin Photosensitizers and Their Stabilized Gold Nanoparticles as Promising Anticancer Agents. Int. J. Mol. Sci. 2008, 9, 864-871.

AMA Style

Demberelnyamba D., Ariunaa M., Shim Y.K. Newly Synthesized Water Soluble Cholinium-Purpurin Photosensitizers and Their Stabilized Gold Nanoparticles as Promising Anticancer Agents. International Journal of Molecular Sciences. 2008; 9(5):864-871.

Chicago/Turabian Style

Demberelnyamba, Dorjnamjin; Ariunaa, Mama; Shim, Young K. 2008. "Newly Synthesized Water Soluble Cholinium-Purpurin Photosensitizers and Their Stabilized Gold Nanoparticles as Promising Anticancer Agents." Int. J. Mol. Sci. 9, no. 5: 864-871.

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