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Int. J. Mol. Sci. 2008, 9(5), 864-871; doi:10.3390/ijms9050864
Article

Newly Synthesized Water Soluble Cholinium-Purpurin Photosensitizers and Their Stabilized Gold Nanoparticles as Promising Anticancer Agents

,  and *
PDT Research Institute, School of Nano System Engineering, Inje University, Gimhae, Korea
* Author to whom correspondence should be addressed.
Received: 6 February 2008 / Revised: 15 May 2008 / Accepted: 19 May 2008 / Published: 23 May 2008
(This article belongs to the Special Issue Natural Compounds for Cancer Treatment and Prevention)
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Abstract

For possible future use in Photodynamic Therapy (PDT) and/or Photothermal Therapy (PTT) of cancer and screening of cancer cells a new type of ionic liquid photosensitizer –Cholinium-Purpurin-18 (Chol-Pu-18) – was synthesized and small gold (Au) nanoparticles, stabilized by this photosensitizer were prepared without adding any particular reducing agents and CTAB. UV-Vis spectroscopy and Transmission Electron Microscopy (TEM) were used for characterization of the nanoparticles and FAB-MS and NMR of the ionic liquid choline hydroxide, purpurin carboxylate and their ionic liquid type of photosensitizer were obtained.
Keywords: Ionic liquid type photosensitizers; choline; purpurin-18; cholinium-purpurin- 18; gold nanoparticles; anticancer agents Ionic liquid type photosensitizers; choline; purpurin-18; cholinium-purpurin- 18; gold nanoparticles; anticancer agents
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Demberelnyamba, D.; Ariunaa, M.; Shim, Y.K. Newly Synthesized Water Soluble Cholinium-Purpurin Photosensitizers and Their Stabilized Gold Nanoparticles as Promising Anticancer Agents. Int. J. Mol. Sci. 2008, 9, 864-871.

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