The Role of miRNAs in Virus-Mediated Oncogenesis
AbstractTo date, viruses are reported to be responsible for more than 15% of all tumors worldwide. The oncogenesis could be influenced directly by the activity of viral oncoproteins or by the chronic infection or inflammation. The group of human oncoviruses includes Epstein–Barr virus (EBV), human papillomavirus (HPV), hepatitis B virus (HBV), hepatitis C virus (HCV), human herpesvirus 8 (HHV-8) or polyomaviruses, and transregulating retroviruses such as HIV or HTLV-1. Most of these viruses express short noncoding RNAs called miRNAs to regulate their own gene expression or to influence host gene expression and thus contribute to the carcinogenic processes. In this review, we will focus on oncogenic viruses and summarize the role of both types of miRNAs, viral as well as host’s, in the oncogenesis. View Full-Text
Share & Cite This Article
Vojtechova, Z.; Tachezy, R. The Role of miRNAs in Virus-Mediated Oncogenesis. Int. J. Mol. Sci. 2018, 19, 1217.
Vojtechova Z, Tachezy R. The Role of miRNAs in Virus-Mediated Oncogenesis. International Journal of Molecular Sciences. 2018; 19(4):1217.Chicago/Turabian Style
Vojtechova, Zuzana; Tachezy, Ruth. 2018. "The Role of miRNAs in Virus-Mediated Oncogenesis." Int. J. Mol. Sci. 19, no. 4: 1217.
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.