Epigenetics and MicroRNAs in Cancer
AbstractThe ability to reprogram the transcriptional circuitry by remodeling the three-dimensional structure of the genome is exploited by cancer cells to promote tumorigenesis. This reprogramming occurs because of hereditable chromatin chemical modifications and the consequent formation of RNA-protein-DNA complexes that represent the principal actors of the epigenetic phenomena. In this regard, the deregulation of a transcribed non-coding RNA may be both cause and consequence of a cancer-related epigenetic alteration. This review summarizes recent findings that implicate microRNAs in the aberrant epigenetic regulation of cancer cells. View Full-Text
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Ramassone, A.; Pagotto, S.; Veronese, A.; Visone, R. Epigenetics and MicroRNAs in Cancer. Int. J. Mol. Sci. 2018, 19, 459.
Ramassone A, Pagotto S, Veronese A, Visone R. Epigenetics and MicroRNAs in Cancer. International Journal of Molecular Sciences. 2018; 19(2):459.Chicago/Turabian Style
Ramassone, Alice; Pagotto, Sara; Veronese, Angelo; Visone, Rosa. 2018. "Epigenetics and MicroRNAs in Cancer." Int. J. Mol. Sci. 19, no. 2: 459.
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