Effects of Highly Polluted Environment on Sperm Telomere Length: A Pilot Study
AbstractHigh environmental pressure may impair male fertility by affecting sperm quality, but the real effect remains controversial. Herein, we assessed the influence of environmental exposure on telomere length (TL) in both leukocytes (LTL) and sperm cells (STL). A pilot biomonitoring study was conducted in 112 clinically healthy, normospermic men living in various areas of Campania region (South of Italy) with high (n = 57, High Group) or low (n = 55, Low Group) environmental pressure. TL analysis was assessed by quantitative real time-PCR. STL was not significantly correlated with either age (p = 0.6) or LTL (p = 0.7), but was significantly longer in the High Group compared with the Low Group (p = 0.04). No significant difference was observed between leukocyte TL in the High or Low Group. Our results showed that male residents in areas with high environment exposure had a significant increase in STL. This finding supports the view that the human semen is a sentinel biomarker of environmental exposure. View Full-Text
Scifeed alert for new publicationsNever miss any articles matching your research from any publisher
- Get alerts for new papers matching your research
- Find out the new papers from selected authors
- Updated daily for 49'000+ journals and 6000+ publishers
- Define your Scifeed now
Vecoli, C.; Montano, L.; Borghini, A.; Notari, T.; Guglielmino, A.; Mercuri, A.; Turchi, S.; Andreassi, M.G. Effects of Highly Polluted Environment on Sperm Telomere Length: A Pilot Study. Int. J. Mol. Sci. 2017, 18, 1703.
Vecoli C, Montano L, Borghini A, Notari T, Guglielmino A, Mercuri A, Turchi S, Andreassi MG. Effects of Highly Polluted Environment on Sperm Telomere Length: A Pilot Study. International Journal of Molecular Sciences. 2017; 18(8):1703.Chicago/Turabian Style
Vecoli, Cecilia; Montano, Luigi; Borghini, Andrea; Notari, Tiziana; Guglielmino, Antonino; Mercuri, Antonella; Turchi, Stefano; Andreassi, Maria G. 2017. "Effects of Highly Polluted Environment on Sperm Telomere Length: A Pilot Study." Int. J. Mol. Sci. 18, no. 8: 1703.
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.