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Int. J. Mol. Sci. 2017, 18(7), 1403; doi:10.3390/ijms18071403

Plant Lectins as Medical Tools against Digestive System Cancers

1
Facultad de Ciencias Naturales, Universidad Autónoma de Querétaro, Santiago de Querétaro 76230, Querétaro, Mexico
2
Unidad de Bioquímica y Biotecnología de Plantas, CINVESTAV Unidad Irapuato, Irapuato 36821, Guanajuato, Mexico
*
Author to whom correspondence should be addressed.
Received: 26 April 2017 / Revised: 21 June 2017 / Accepted: 25 June 2017 / Published: 3 July 2017
(This article belongs to the Special Issue Plant Lectins: From Model Species to Crop Plants)
View Full-Text   |   Download PDF [295 KB, uploaded 11 July 2017]   |  

Abstract

Digestive system cancers—those of the esophagus, stomach, small intestine, colon-rectum, liver, and pancreas—are highly related to genetics and lifestyle. Most are considered highly mortal due to the frequency of late diagnosis, usually in advanced stages, caused by the absence of symptoms or masked by other pathologies. Different tools are being investigated in the search of a more precise diagnosis and treatment. Plant lectins have been studied because of their ability to recognize and bind to carbohydrates, exerting a variety of biological activities on animal cells, including anticancer activities. The present report integrates existing information on the activity of plant lectins on various types of digestive system cancers, and surveys the current state of research into their properties for diagnosis and selective treatment. View Full-Text
Keywords: cancer; diagnosis tools; digestive system; plant lectins; therapeutic tools cancer; diagnosis tools; digestive system; plant lectins; therapeutic tools
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Estrada-Martínez, L.E.; Moreno-Celis, U.; Cervantes-Jiménez, R.; Ferriz-Martínez, R.A.; Blanco-Labra, A.; García-Gasca, T. Plant Lectins as Medical Tools against Digestive System Cancers. Int. J. Mol. Sci. 2017, 18, 1403.

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