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Int. J. Mol. Sci. 2017, 18(6), 1242; doi:10.3390/ijms18061242

Legume Lectins: Proteins with Diverse Applications

1
CONACyT-Universidad de Sonora, Blvd. Luis Encinas y Rosales, Hermosillo, Sonora 83000, Mexico
2
Coordinacion de Ciencia de los Alimentos, Centro de Investigacion en Alimentacion y Desarrollo, A.C., Apartado Postal 1735, Hermosillo, Sonora 83304, Mexico
*
Author to whom correspondence should be addressed.
Academic Editor: Els Van Damme
Received: 29 April 2017 / Revised: 1 June 2017 / Accepted: 5 June 2017 / Published: 12 June 2017
(This article belongs to the Special Issue Plant Lectins: From Model Species to Crop Plants)
View Full-Text   |   Download PDF [831 KB, uploaded 12 June 2017]   |  

Abstract

Lectins are a diverse class of proteins distributed extensively in nature. Among these proteins; legume lectins display a variety of interesting features including antimicrobial; insecticidal and antitumor activities. Because lectins recognize and bind to specific glycoconjugates present on the surface of cells and intracellular structures; they can serve as potential target molecules for developing practical applications in the fields of food; agriculture; health and pharmaceutical research. This review presents the current knowledge of the main structural characteristics of legume lectins and the relationship of structure to the exhibited specificities; provides an overview of their particular antimicrobial; insecticidal and antitumor biological activities and describes possible applications based on the pattern of recognized glyco-targets. View Full-Text
Keywords: lectin; legume; insecticidal; antimicrobial; cancer lectin; legume; insecticidal; antimicrobial; cancer
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Lagarda-Diaz, I.; Guzman-Partida, A.M.; Vazquez-Moreno, L. Legume Lectins: Proteins with Diverse Applications. Int. J. Mol. Sci. 2017, 18, 1242.

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