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Int. J. Mol. Sci. 2017, 18(4), 897; doi:10.3390/ijms18040897

Health Effects of Psidium guajava L. Leaves: An Overview of the Last Decade

1
Department of Analytical Chemistry, Faculty of Sciences, University of Granada, Avd. Fuentenueva s/n, 18071 Granada, Spain
2
Functional Food Research and Development Center, Health Science Technological Park, Avd. Del Conocimiento, Bioregion Building, 18100 Granada, Spain
3
Department of Nutrition and Food Science, University of Granada, Campus of Cartuja, 18071 Granada, Spain
*
Author to whom correspondence should be addressed.
Academic Editor: Maurizio Battino
Received: 13 March 2017 / Revised: 17 April 2017 / Accepted: 19 April 2017 / Published: 24 April 2017
View Full-Text   |   Download PDF [824 KB, uploaded 24 April 2017]   |  

Abstract

Today, there is increasing interest in discovering new bioactive compounds derived from ethnomedicine. Preparations of guava (Psidium guajava L.) leaves have traditionally been used to manage several diseases. The pharmacological research in vitro as well as in vivo has been widely used to demonstrate the potential of the extracts from the leaves for the co-treatment of different ailments with high prevalence worldwide, upholding the traditional medicine in cases such as diabetes mellitus, cardiovascular diseases, cancer, and parasitic infections. Moreover, the biological activity has been attributed to the bioactive composition of the leaves, to some specific phytochemical subclasses, or even to individual compounds. Phenolic compounds in guava leaves have been credited with regulating blood-glucose levels. Thus, the aim of the present review was to compile results from in vitro and in vivo studies carried out with guava leaves over the last decade, relating the effects to their clinical applications in order to focus further research for finding individual bioactive compounds. Some food applications (guava tea and supplementary feed for aquaculture) and some clinical, in vitro, and in vivo outcomes are also included. View Full-Text
Keywords: Psidium guajava L. (guava) leaves; traditional medicine; in vitro; in vivo; phenolic compounds; pharmacology Psidium guajava L. (guava) leaves; traditional medicine; in vitro; in vivo; phenolic compounds; pharmacology
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Díaz-de-Cerio, E.; Verardo, V.; Gómez-Caravaca, A.M.; Fernández-Gutiérrez, A.; Segura-Carretero, A. Health Effects of Psidium guajava L. Leaves: An Overview of the Last Decade. Int. J. Mol. Sci. 2017, 18, 897.

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