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Int. J. Mol. Sci. 2017, 18(12), 2653; https://doi.org/10.3390/ijms18122653

The Role of Vitamin D in Non-Scarring Alopecia

Chair and Department of Dermatology, Venereology and Paediatric Dermatology, Medical University of Lublin, Radziwiłłowska 13, 20-080 Lublin, Poland
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Received: 29 October 2017 / Revised: 2 December 2017 / Accepted: 3 December 2017 / Published: 7 December 2017
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Abstract

Non-scarring hair loss is a common problem that affects both male and female patients. Since any disturbances in the hair follicle cycle may lead to hair shedding, or alopecia, it is not surprising that the possible role of vitamin D in alopecia was investigated in many studies. Vitamin D has been shown to have many important functions. A growing body of evidence shows that vitamin D and its receptor are responsible for maintaining not only calcium homeostasis but also skin homeostasis. Moreover, vitamin D could also regulate cutaneous innate and adaptive immunity. This paper presents a review of current literature considering the role of vitamin D in alopecia areata, telogen effluvium, and female pattern hair loss. The majority of studies revealed decreased serum 25-hydroxyvitamin D levels in patients with different types of non-scarring alopecia, which could suggest its potential role in the pathogenesis of hair loss. According to the authors, vitamin D supplementation could be a therapeutic option for patients with alopecia areata, female pattern hair loss, or telogen effluvium. However, further studies on a larger group of patients are required. View Full-Text
Keywords: vitamin D; vitamin D receptor; alopecia vitamin D; vitamin D receptor; alopecia
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Gerkowicz, A.; Chyl-Surdacka, K.; Krasowska, D.; Chodorowska, G. The Role of Vitamin D in Non-Scarring Alopecia. Int. J. Mol. Sci. 2017, 18, 2653.

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