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Int. J. Mol. Sci. 2016, 17(5), 688; doi:10.3390/ijms17050688

Varicella Skin Complications in Childhood: A Case Series and a Systematic Review of the Literature

1
Department of Pediatrics, Pediatric and Infectious Diseases Unit, Bambino Gesù Children’s Hospital, IRCCS, Piazza Sant’Onofrio 4, 00165 Rome, Italy
2
Internal Medicine and Therapeutics Department, Pediatrics and Adolescentology Unit, University of Pavia, Fondazione IRCCS San Matteo, Viale Golgi 19, 27100 Pavia, Italy
3
Multifactorial Disease and Complex Phenotype Research Area, Bambino Gesù Children’s Hospital, IRCCS, Piazza Sant’Onofrio 4, 00165 Rome, Italy
4
Department of Pediatrics, Dermatologocical Unit, Bambino Gesù Children’s Hospital, IRCCS, Piazza Sant’Onofrio 4, 00165 Rome, Italy
*
Author to whom correspondence should be addressed.
Academic Editor: Susanna Esposito
Received: 10 March 2016 / Revised: 2 May 2016 / Accepted: 3 May 2016 / Published: 6 May 2016
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Abstract

Even if varicella is generally considered a harmless disease in childhood, severe complications may occur. We examined varicella skin complications (VSCs) in hospitalized immunologically healthy children, over a nine-year period. We also systematically analyzed previous reports to calculate the rate of VSCs in the literature. VSCs occurred in 16.4% of children hospitalized for varicella. This figure is in accordance with the literature, as the range of VSCs was 2.6%–41.2%. Skin complications may represent determinants of hospitalization and of other indirect costs in young children. View Full-Text
Keywords: varicella; children; skin complication; hospitalization varicella; children; skin complication; hospitalization
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MDPI and ACS Style

Bozzola, E.; Bozzola, M.; Krzysztofiak, A.; Tozzi, A.E.; El Hachem, M.; Villani, A. Varicella Skin Complications in Childhood: A Case Series and a Systematic Review of the Literature. Int. J. Mol. Sci. 2016, 17, 688.

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